Thermo Fisher Scientific
Thermo Fisher Scientific is a globally renowned leader in scientific solutions, playing a critical role in the wastewater surveillance (WWS) market by supplying essential instruments, reagents, and molecular diagnostic technologies. The company’s WWS portfolio is anchored by its industry-leading platforms for quantitative PCR (qPCR), digital PCR (dPCR), and next-generation sequencing (NGS), which are fundamental tools used worldwide to detect pathogens, monitor antimicrobial resistance (AMR), and track emerging viral variants in wastewater. Thermo Fisher’s strategic advantage is its ability to provide an integrated and comprehensive workflow—from the initial steps of sample collection and concentration to the final stages of molecular analysis and cloud-based data interpretation. This end-to-end solution ensures high accuracy and efficiency for public health and environmental labs. The company is actively invested in R&D to continuously improve the sensitivity and throughput of its WWS products, reinforcing its leadership position and enabling public health agencies and research institutions globally to respond rapidly and effectively to infectious disease threats through advanced, reliable scientific infrastructure.
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IDEXX Laboratories
IDEXX Laboratories is a leading global provider of diagnostic and testing solutions, with a dominant presence in the water and wastewater testing sector, making it a pivotal player in the wastewater surveillance (WWS) market. The company is widely recognized for its core expertise in microbiological testing methods and offers a robust, broad portfolio of advanced diagnostic kits, instruments, and reagents. These products are specifically designed for the detection of pathogens and contaminants in wastewater, including critical public health threats like SARS-CoV-2. IDEXX strategically invests heavily in research and development to boost detection sensitivity, streamline complex laboratory workflows, and enhance automation in sample processing, which is essential for high-throughput WWS programs. With a strong global distribution network, significant brand recognition, and comprehensive training programs, IDEXX is a trusted and essential partner for public health agencies and laboratories across the world, continuously advancing the tools necessary for effective global disease monitoring programs.
Verily Life Sciences
Verily Life Sciences, LLC, a subsidiary of Alphabet, is a major technology-driven player in the wastewater surveillance (WWS) market, distinguished as a leader in the laboratory science behind wastewater-based epidemiology (WBE). The company’s core mission in WWS is to provide high-quality, fast-turnaround monitoring data to help communities track and prevent the spread of infectious diseases. Verily is a key operational partner in the U.S. CDC’s National Wastewater Surveillance System (NWSS), running a high-throughput, state-of-the-art laboratory that leverages automation to optimize efficiency for hundreds of sites across the United States. Verily offers comprehensive assays currently capable of testing for over 30 pathogens, with continuous research to identify more. Furthermore, the company extends its value beyond testing by offering an easy-to-use online tool for clients, providing clear visualization and monitoring of viral levels, effectively translating complex data into actionable public health intelligence for researchers, clinicians, and health departments.
Biobot Analytics
Biobot Analytics is a pioneering company that provides a sophisticated wastewater intelligence platform, positioning itself as a leader in the services and testing segment of the wastewater surveillance (WWS) market. The company’s platform offers real-time, privacy-first health intelligence by tracking not only a broad range of pathogens, including SARS-CoV-2, Influenza A, and RSV, but also drugs such as Fentanyl and Cocaine. Biobot is known for its consistent data collection and analysis method, which allows for a comprehensive and granular national picture of community health trends. Crucially, Biobot delivers variant sequencing to monitor the emergence of new viral strains. Their wastewater data has proven to be an effective early warning system, showing a high correlation with clinical data and often providing predictive insights up to 1-2 weeks ahead of publicly available clinical reports. Biobot’s data is leveraged by government agencies and healthcare systems to make faster, more informed decisions about public health interventions.
Bio-Rad Laboratories
Bio-Rad Laboratories, Inc. is a globally recognized leader in life sciences research and clinical diagnostics with substantial contributions to the wastewater surveillance (WWS) domain. As a major market player, Bio-Rad specializes in providing highly sensitive molecular testing solutions, primarily leveraging its proprietary Droplet Digital PCR (ddPCR) technology. This technology is critical for WWS because it allows for the ultra-sensitive and absolute quantification of minute amounts of nucleic acids, which is necessary for accurate viral load determination in complex wastewater matrices. Bio-Rad offers a range of ddPCR and RT-PCR assays specifically developed for the surveillance of pathogens, including SARS-CoV-2 and its emerging variants. Beyond infectious disease monitoring, the company’s water quality testing products are used by laboratories to detect and enumerate pathogenic bacteria and quality indicators, underscoring its foundational role in providing the essential instrumentation, kits, and assays for both environmental and public health-focused wastewater analysis.
Eurofins Scientific
Eurofins Scientific is a major global player in the wastewater surveillance (WWS) market, primarily through its extensive network of laboratory services. Operating as a large Contract Research Organization (CRO)-style testing group, Eurofins offers comprehensive, end-to-end WWS services that span the entire process from sample collection and logistics to high-end molecular analysis and reporting. The company serves public health agencies and utilities globally, purchasing and utilizing advanced analytical instruments, such as qPCR, dPCR, and NGS platforms, from major manufacturers. Eurofins’ strength lies in its ability to offer scalable, reliable, and standardized testing for complex targets, including pathogens and the tracking of antimicrobial resistance (AMR) genes. This operational model allows governmental and commercial entities to outsource the technical complexities of WWS, ensuring they receive consistent, high-quality epidemiological data without the need for significant internal lab infrastructure investment. This capability has made Eurofins a trusted partner in large-scale national and regional surveillance programs.
Hach (A Danaher Company)
Hach, a company operating under the Danaher Corporation umbrella, is a key component of the wastewater surveillance (WWS) market, specializing in the provision of analytical instrumentation and equipment. As a leading supplier in the product market, Hach is renowned for its advanced samplers, sensors, and laboratory instruments that are crucial for both the routine monitoring and targeted surveillance phases of wastewater-based epidemiology (WBE). These instruments provide the necessary physical and chemical data, as well as the essential sample collection, that precedes molecular analysis. Hach’s strong reputation is built on product reliability, a comprehensive field service network, and continuous product innovation aimed at simplifying and automating the front-end of the WWS workflow. As a preferred choice for municipalities, utilities, and research organizations worldwide, Hach ensures the fundamental infrastructure is in place for consistent and reliable sample acquisition, providing the backbone for the subsequent high-tech molecular diagnostic steps performed by other WWS players.
ZYMO RESEARCH
ZYMO RESEARCH is recognized as a Global Leader in Wastewater Surveillance, specializing in molecular biology solutions with a particular focus on optimizing the crucial front-end steps of wastewater-based epidemiology (WBE). The company is known for delivering industry-leading solutions for reliable sample preparation and high-sensitivity molecular analysis, which are critical given the low concentrations of target material in wastewater. Zymo Research offers a fully integrated workflow and expert services, partnering with top public health institutions to ensure accurate and reproducible results for infectious disease monitoring and outbreak prevention. Their product line includes advanced tools for DNA and RNA purification, as well as Next-Generation Sequencing (NGS) services, enabling precise species-level pathogen identification and accurate monitoring of antimicrobial resistance (AMR). Furthermore, Zymo provides VirSieve, an open-source bioinformatic tool for variant calling on complex samples, solidifying its role as an innovator in both the consumables and software components of the global WWS landscape.
SGS
SGS is a world-leading company in inspection, verification, testing, and certification, with a significant involvement in the wastewater surveillance (WWS) sector as a comprehensive service provider. Leveraging its extensive global network of laboratories and offices, SGS offers specialized wastewater epidemiological surveillance services, managing the entire logistics chain from almost any location to a suitable testing lab. Their in-house laboratory workflows are optimized for sample concentration and the extraction of low-concentration viral genetic material, aligning with established COVID surveillance methods while screening for multiple viruses. SGS provides expertise in wastewater sampling, including the use of automatic water sampling equipment, and advises clients on optimal strategies. A key aspect of their service is the ability to provide customized data visualization dashboards for clients, along with the capacity to assess and apply data normalization steps, ensuring the final surveillance data is accurate, reliable, and directly actionable for public health officials globally.
AdvanSentinel (Shionogi & Shimadzu Joint Venture)
AdvanSentinel is a joint venture established in January 2022 between major pharmaceutical company Shionogi and scientific instrument maker Shimadzu Corporation, positioning itself as a key regional player in the wastewater surveillance (WWS) market in Japan. The partnership aims to build an “All-Japan system” for public health risk assessment by combining the wastewater monitoring networks and respective expertise of both founding companies. Shionogi and its partners developed a proprietary, highly sensitive detection system, which is reported to be about 100 times more sensitive than conventional methods. This system is crucial for the quantitative analysis of viruses like SARS-CoV-2 in low-prevalence areas using quantitative PCR (qPCR). AdvanSentinel offers comprehensive WWS services to municipalities, providing regular sample collection, rapid analysis results, and optional mutation analysis using Next-Generation Sequencing (NGS) for the identification and tracking of mutant viral strains, thereby translating their scientific strengths into a national public health early warning system.
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