Pfizer
Pfizer is a major pharmaceutical company globally recognized for its commitment to fighting antimicrobial resistance (AMR), largely through its extensive surveillance programs. Its flagship initiative in this area is the Antimicrobial Testing Leadership and Surveillance (ATLAS) database, which is one of the largest global surveillance programs for AMR. ATLAS provides publicly accessible, interactive, and extensive data on emerging bacterial and fungal resistance patterns and sensitivity to antibiotics across more than 60 countries. By integrating data from previous surveillance programs (TEST, AWARE, INFORM, and SENTRY for antifungal data), Pfizer offers a unique, comprehensive resource for researchers and healthcare providers. The data is often shared openly via the ATLAS website and the Wellcome Trust’s AMR Register, supporting timely decision-making for antibiotic stewardship and infection control programs worldwide.
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Illumina
Illumina is a global technological leader specializing in array-based technologies and DNA sequencing. In the context of Antimicrobial Resistance (AMR) surveillance, Illumina is pivotal as it provides the Next-Generation Sequencing (NGS) platforms essential for rapid and detailed microbial genomic analysis. NGS allows for the comprehensive genomic insights needed for AMR-related studies, including microbial whole-genome sequencing (WGS) to determine origins, identification, and evolutionary behavior of pathogens without needing specific probes. Illumina’s solutions, which include NGS-based workflows like shotgun metagenomics and hybrid capture, are critical for public health surveillance, including wastewater, tuberculosis, and genomic surveillance. By offering specialized products like the AmpliSeq for Illumina Antimicrobial Resistance Panel, the company enables high-resolution detection of AMR genes, significantly advancing the capability to monitor and track the emergence and spread of resistant microbes.
bioMérieux
BioMérieux is a European company specializing in in vitro diagnostics, and it is a leading player in the Antimicrobial Susceptibility Testing (AST) and surveillance market. The company develops and provides innovative solutions designed to make microbial resistance detection faster and more accurate, which is crucial for effective surveillance. BioMérieux’s comprehensive portfolio is continuously enhanced to provide detailed antimicrobial susceptibility profiles, helping clinicians optimize appropriate therapies against growing resistance challenges. Notable systems include the VITEK® REVEAL™ AST System, which is designed to detect antimicrobial resistance in positive blood culture samples. BioMérieux’s commitment to sophisticated diagnostic technologies helps healthcare facilities quickly identify pathogens and resistance markers, enabling timely treatment decisions and contributing significantly to global AMR surveillance efforts.
Becton, Dickinson and Company (BD)
Becton, Dickinson and Company (BD) is a major global medical technology company that operates extensively within the diagnostics sector, making it a key contributor to Antimicrobial Resistance (AMR) surveillance through its advanced diagnostic systems. BD offers a suite of solutions focused on increasing diagnostic precision and speed, which are essential factors in monitoring and controlling resistant infections. Innovative systems like the BD Phoenix and solutions leveraging the BD Bruker MALDI Biotyper are utilized to provide fast and precise susceptibility profiles. These tools are instrumental for healthcare professionals, assisting them in making appropriate treatment decisions based on rapid data acquisition regarding microbial susceptibility. BD’s continuous advancement in diagnostic technology supports the real-time tracking of emerging resistance trends, thereby improving patient outcomes and bolstering global surveillance infrastructure against AMR.
Thermo Fisher Scientific
Thermo Fisher Scientific is a globally recognized provider of scientific solutions, playing a pivotal role in the Antimicrobial Susceptibility Testing (AST) and surveillance markets. The company provides a broad diagnostics suite capable of handling the complex challenges associated with microbial resistance, offering instruments, reagents, and services essential for detailed analysis. Thermo Fisher’s offerings are integral to various surveillance methods, including high-quality diagnostics that help healthcare professionals remain ahead of emerging resistance trends. Their products support the timely and accurate diagnostic information needed for effective patient care and public health tracking. By focusing on innovation and high-quality diagnostic platforms, Thermo Fisher contributes significantly to the global fight against antibiotic resistance by strengthening the tools available for detection and monitoring.
Merck (MSD)
Merck, known as MSD outside the US and Canada, is a global pharmaceutical leader that actively supports efforts to track the spread of Antimicrobial Resistance (AMR). Since 2002, MSD has operated one of the world’s largest and longest-running surveillance studies, the Study for Monitoring Antimicrobial Resistance Trends (SMART). This program has collected extensive data on over 200,000 isolates from 217 sites across 63 countries, monitoring respiratory, complicated intra-abdominal, and urinary tract infections. SMART data is made publicly available to the scientific research community, including innovators working on rapid diagnostics and IT products. MSD’s commitment extends beyond data collection; they also work with hospitals to implement clinical treatment pathways based on local microbiological data, making them a crucial contributor to both surveillance and antimicrobial stewardship.
Danaher Corporation
Danaher Corporation is a diversified science and technology conglomerate whose subsidiaries are significant players in the Antimicrobial Resistance (AMR) surveillance market. Through companies like Cepheid and Beckman Coulter, Danaher provides sophisticated diagnostic technologies crucial for addressing the AMR challenge. Cepheid is known for its rapid molecular diagnostics platforms (e.g., GeneXpert), which enable swift identification of pathogens and resistance markers at the point of care. Beckman Coulter offers systems like the MicroScan for accurate susceptibility testing. Danaher’s emphasis is on providing innovative and precise diagnostic testing to support the global effort against rising antimicrobial resistance, improving patient outcomes and overall efficiency in healthcare delivery by ensuring fast and reliable identification of resistant strains.
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