Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 4
Introduction 5
Global Markets Direct Report Coverage 5
Pol Polyprotein Overview 6
Therapeutics Development 7
Pol Polyprotein - Products under Development by Stage of Development 7
Pol Polyprotein - Products under Development by Therapy Area 8
Pol Polyprotein - Products under Development by Indication 9
Pol Polyprotein - Pipeline Products Glance 10
Late Stage Products 10
Early Stage Products 11
Pol Polyprotein - Products under Development by Companies 12
Pol Polyprotein - Products under Development by Universities/Institutes 14
Pol Polyprotein - Therapeutics Assessment 16
Assessment by Monotherapy/Combination Products 16
Assessment by Route of Administration 17
Assessment by Molecule Type 19
Pol Polyprotein - Companies Involved in Therapeutics Development 21
GeoVax Labs, Inc. 21
Inovio Pharmaceuticals, Inc. 22
Johnson & Johnson 23
Pol Polyprotein - Drug Profiles 24
GOVXB-11 - Drug Profile 24
Product Description 24
Mechanism Of Action 24
R&D Progress 24
GOVXC-11 - Drug Profile 27
Product Description 27
Mechanism Of Action 27
R&D Progress 27
GOVXC-21 - Drug Profile 28
Product Description 28
Mechanism Of Action 28
R&D Progress 28
HIV [serotype Ad26] (tetravalent) vaccine - Drug Profile 29
Product Description 29
Mechanism Of Action 29
R&D Progress 29
HIV-1 (bivalent) vaccine - Drug Profile 30
Product Description 30
Mechanism Of Action 30
R&D Progress 30
HIV-1 vaccine 11 - Drug Profile 31
Product Description 31
Mechanism Of Action 31
R&D Progress 31
HIV-1 vaccine 5 - Drug Profile 32
Product Description 32
Mechanism Of Action 32
R&D Progress 32
PENNVAX-B - Drug Profile 33
Product Description 33
Mechanism Of Action 33
R&D Progress 33
PENNVAX-GP - Drug Profile 36
Product Description 36
Mechanism Of Action 36
R&D Progress 36
Pol Polyprotein - Dormant Projects 38
Pol Polyprotein - Featured News & Press Releases 39
May 18, 2016: GeoVax Observes HIV Vaccine Awareness Day And Prepares for Next Human Clinical Trial of GOVX-B11 39
Apr 14, 2016: GeoVax Awarded $1.4M NIH Grant 40
Mar 07, 2016: Strong Protection Elicited by an Immunodeficiency Virus Vaccine in Non-Human Primates 40
Sep 08, 2015: Inovio Pharmaceuticals Announces First Patient Dosed With Universal HIV Vaccine 41
Apr 14, 2015: GeoVax to Seek Dual Pathway for Advancing Its HIV Preventive Vaccine 42
Apr 09, 2015: GeoVax Provides Details of Presentation at World Vaccine Congress 42
Apr 01, 2015: GeoVax Provides Update on Its HIV Vaccine Program 43
Mar 16, 2015: Inovio Pharmaceuticals and Academic Collaborators Receive $16 Million HIV Grant From National Institute of Allergy and Infectious Diseases 44
Jan 06, 2015: Inovio Pharmaceuticals HIV Immunotherapy Shows Characteristics Considered Vital to Treating HIV 45
Oct 29, 2014: GeoVax Presents HIV Vaccine Clinical Trial Data 46
Jul 30, 2014: GeoVax Awarded Small Business Innovative Research (SBIR) Grant from National Institutes of Health 47
Jan 23, 2014: GeoVax Announces Publication of Phase 2a Clinical Trial in The Journal of Infectious Diseases 47
Jan 13, 2014: GeoVax Announces Preliminary Top-Line Results for Phase 1 Therapeutic Vaccine Trial in HIV-Infected Patients 48
Oct 09, 2013: GeoVax DNA/MVA Vaccine Elicits Sustained Antibody Responses to HIV 49
Jan 10, 2013: GeoVax Announces Enrollment Completion For Phase I/II Clinical Trial For HIV/AIDS Therapeutic Vaccine 50
Appendix 51
Methodology 51
Coverage 51
Secondary Research 51
Primary Research 51
Expert Panel Validation 51
Contact Us 51
Disclaimer 52
List of Tables
Number of Products under Development for, H1 2016 7
Number of Products under Development by Therapy Area, H1 2016 8
Number of Products under Development by Indication, H1 2016 9
Comparative Analysis by Late Stage Development, H1 2016 10
Comparative Analysis by Early Stage Products, H1 2016 11
Number of Products under Development by Companies, H1 2016 12
Products under Development by Companies, H1 2016 13
Number of Products under Investigation by Universities/Institutes, H1 2016 14
Products under Investigation by Universities/Institutes, H1 2016 15
Assessment by Monotherapy/Combination Products, H1 2016 16
Number of Products by Stage and Route of Administration, H1 2016 18
Number of Products by Stage and Molecule Type, H1 2016 20
Pipeline by GeoVax Labs, Inc., H1 2016 21
Pipeline by Inovio Pharmaceuticals, Inc., H1 2016 22
Pipeline by Johnson & Johnson, H1 2016 23
Dormant Projects, H1 2016 38
List of Figures
Number of Products under Development for, H1 2016 7
Number of Products under Development by Indication, H1 2016 9
Comparative Analysis by Early Stage Products, H1 2016 11
Assessment by Monotherapy/Combination Products, H1 2016 16
Number of Products by Routes of Administration, H1 2016 17
Number of Products by Stage and Routes of Administration, H1 2016 17
Number of Products by Molecule Types, H1 2016 19
Number of Products by Stage and Molecule Type, H1 2016 19