Biomarker Partnering Terms and Agreements

Published: November 2014
No. of Pages: 1048
   

The Biomarker Partnering Terms and Agreements report provides comprehensive understanding and unprecedented access to the biomarker partnering deals and agreements entered into by the worlds leading healthcare companies.

  • Trends in biomarker partnering deals
  • Biomarker partnering agreement structure
  • Biomarker partnering contract documents
  • Top biomarker deals by value
  • Most active biomarker dealmakers

The Biomarker Partnering Terms and Agreements report provides comprehensive understanding and unprecedented access to the biomarker partnering deals and agreements entered into by the worlds leading healthcare companies.

The report provides a detailed understanding and analysis of how and why companies enter biomarker partnering deals. The majority of deals are discovery or development stage whereby the licensee obtains a right or an option right to license the licensors biomarker technology. These deals tend to be multicomponent, starting with collaborative R&D, and commercialization of outcomes.

Understanding the flexibility of a prospective partner’s negotiated deals terms provides critical insight into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of how payments are triggered – contract documents provide this insight where press releases do not.

This report contains over 700 links to online copies of actual biomarker deals and contract documents as submitted to the Securities Exchange Commission by companies and their partners. Contract documents provide the answers to numerous questions about a prospective partner’s flexibility on a wide range of important issues, many of which will have a significant impact on each party’s ability to derive value from the deal.

The initial chapters of this report provide an orientation of biomarker dealmaking and business activities. Chapter 1 provides an introduction to the report, whilst chapter 2 provides an overview of the trends in biomarker dealmaking since 2009, including details of average headline, upfront, milestone and royalty terms.

Chapter 3 provides a review of the leading biomarker deals since 2009. Deals are listed by headline value, signed by big pharma and most active of all biopharma companies. Where the deal has an agreement contract published at the SEC a link provides online access to the contract.

Chapter 4 provides a comprehensive listing of the top 50 big pharma companies with a brief summary followed by a comprehensive listing of biomarker deals as well as contract documents available in the public domain. Where available, each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

Chapter 5 provides a comprehensive and detailed review of biomarker partnering deals signed and announced since January 2009, where a contract document is available in the public domain. The chapter is organized by stage of development at signing, deal type (collaborative R&D, co-promotion, licensing etc), and specific therapy focus. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

Chapter 6 provides a comprehensive and detailed review of biomarker partnering deals signed and announced since January 2009. The chapter is organized by specific biomarker technology type in focus. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

In addition, a comprehensive appendix is provided organized by biomarker partnering company A-Z , stage of development, deal type, therapy area, deal type definitions and biomarker partnering agreements example. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

In conclusion, this report provides everything a prospective dealmaker needs to know about partnering in the research, development and commercialization of biomarker technologies and products.

Biomarker Partnering Terms and Agreements is intended to provide the reader with an in-depth understanding and access to biomarker trends and structure of deals entered into by leading companies worldwide.

Biomarker Partnering Terms and Agreements includes:

  • Trends in biomarker dealmaking in the biopharma industry since 2009
  • Analysis of biomarker deal structure
  • Access to headline, upfront, milestone and royalty data
  • Case studies of real-life biomarker deals
  • Access to several biomarker contract documents
  • The leading biomarker deals by value since 2009
  • Most active biomarker dealmakers since 2009
  • The leading biomarker partnering resources

In Biomarker Partnering Terms and Agreements, the available contracts are listed by:

  • Company A-Z
  • Headline value
  • Stage of development at signing
  • Deal component type
  • Specific therapy target

Each deal title links via weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

The Biomarker Partnering Terms and Agreements report provides comprehensive access to available deals and contract documents for over 700 biomarker deals. Analyzing actual contract agreements allows assessment of the following:

  • What are the precise biomarker rights granted or optioned?
  • What is actually granted by the agreement to the partner company?
  • What exclusivity is granted?
  • What is the payment structure for the deal?
  • How are sales and payments audited?
  • What is the deal term?
  • How are the key terms of the agreement defined?
  • How are IPRs handled and owned?
  • Who is responsible for commercialization?
  • Who is responsible for development, supply, and manufacture?
  • How is confidentiality and publication managed?
  • How are disputes to be resolved?
  • Under what conditions can the deal be terminated?
  • What happens when there is a change of ownership?
  • What sublicensing and subcontracting provisions have been agreed?
  • Which boilerplate clauses does the company insist upon?
  • Which boilerplate clauses appear to differ from partner to partner or deal type to deal type?
  • Which jurisdiction does the company insist upon for agreement law?

Biomarker Partnering Terms and Agreements provides the reader with the following key benefits:

  • In-depth understanding of biomarker deal trends since 2009
  • Analysis of the structure of biomarker agreements with numerous real life case studies
  • Comprehensive access to over 700 actual biomarker deals entered into by the world’s biopharma companies, together with real world clause examples
  • Full listing of biomarker deals by company A-Z, deal value, phase of development, deal type, and therapy focus
  • Identify leading biomarker deals by value since 2009
  • Identify the most active biomarker dealmakers since 2009
  • Detailed access to actual biomarker deals and contracts enter into by the leading fifty big pharma companies
  • Understand the key deal terms companies have agreed in previous deals
  • Undertake due diligence to assess suitability of your proposed deal terms for partner companies

Biomarker Partnering Terms and Agreements

Table of Contents

Executive Summary

Chapter 1 – Introduction

Chapter 2 – Trends in biomarker dealmaking
2.1. Introduction
2.2. Biomarker partnering over the years
2.3. Big pharma biomarker dealmaking activity
2.4. Most active biomarker dealmakers
2.5. Biomarker partnering by deal type
2.6. Biomarker partnering by disease type
2.7 Average deal terms for biomarkers
2.7.1 Biomarker headline values
2.7.2 Biomarker upfront payments
2.7.3 Biomarker milestone payments
2.7.4 Biomarker royalty rates
2.8. The anatomy of biomarker partnering
2.8.1 The anatomy of a biomarker deal
2.8.1.a Case study 1: Kinemed, GlaxoSmithKline- June 2012
2.8.1.b Case study 2: TrovaGene, Columbia University- December 2011

Chapter 3 – Leading biomarker deals
3.1. Introduction
3.2. Top biomarker deals by value

Chapter 4 – Big pharma biomarker deals
4.1. Introduction
4.2. How to use big pharma biomarker partnering deals
4.3. Big pharma biomarker partnering company profiles
Abbott
Amgen
AstraZeneca
Bayer
Biogen Idec
Boehringer Ingelheim
Bristol-Myers Squibb
Celgene
Daiichi Sankyo
Eisai
Eli Lilly
GlaxoSmithKline
Johnson & Johnson
Kyowa Hakko Kirin
Lundbeck
Merck & Co
Merck KGaA
Novartis
Novo Nordisk
Otsuka
Pfizer
Purdue
Roche
Sanofi
Servier
Takeda
Teva

Chapter 5 – Biomarker contracts dealmaking directory
5.1. Introduction
5.2. Biomarker deals with contract by company A-Z
5.3. Biomarker deals with contract by deal type
5.4. Biomarker deals with contract by therapy area

Chapter 6 – Biomarker dealmaking by technology type
6.1. Introduction
6.2. Deals by biomarker type
Biomarkers

Chapter 7 – Biomarker partnering resource center
7.1. Online biomarker partnering
7.2. Biomarker partnering events
7.3. Further reading on biomarker dealmaking

About Wildwood Ventures
Current Partnering
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Appendices
Appendix 1 – Biomarker partnering by company A-Z
Appendix 2 - Biomarker partnering by stage of development
Appendix 3 - Biomarker partnering by deal type
Appendix 4 - Biomarker partnering by therapy area

List of Figures

Figure 1: Biomarker partnering since 2009
Figure 2: Big pharma – top 50 – biomarker deals 2009 to 2014
Figure 3: Big pharma biomarker deal frequency – 2009 to 2014
Figure 4: Active biomarker dealmaking activity– 2009 to 2014
Figure 5: Biomarker partnering by deal type since 2009
Figure 6: Biomarker partnering by disease type since 2009
Figure 7: Biomarker partnering by oncology target since 2009
Figure 8: Biomarker deals with a headline value by year- 2014
Figure 9: Biomarker deals with a headline value by year- 2013
Figure 10: Biomarker deals with a headline value by year- 2012
Figure 11: Biomarker deals with a headline value by year- 2011
Figure 12: Biomarker deals with a headline value by year- 2010
Figure 13: Biomarker deals with a headline value by year- 2009
Figure 14: Summary median headline value by year, 2009-2014
Figure 15: Biomarker deals with an upfront value by year- 2014
Figure 16: Biomarker deals with an upfront value by year- 2013
Figure 17: Biomarker deals with an upfront value by year- 2012
Figure 18: Biomarker deals with an upfront value by year- 2011
Figure 19: Biomarker deals with an upfront value by year- 2010
Figure 20: Biomarker deals with an upfront value by year- 2009
Figure 21: Summary median upfront value by year, 2009-2014
Figure 22: Biomarker deals with a milestone value by year- 2014
Figure 23: Biomarker deals with a milestone value by year- 2013
Figure 24: Biomarker deals with a milestone value by year- 2012
Figure 25: Biomarker deals with a milestone value by year- 2011
Figure 26: Biomarker deals with a milestone value by year- 2010
Figure 27: Biomarker deals with a milestone value by year- 2009
Figure 28: Biomarker deals with a royalty rate by year- 2014
Figure 29: Biomarker deals with a royalty rate by year- 2013
Figure 30: Biomarker deals with a royalty rate by year- 2012
Figure 31: Biomarker deals with a royalty rate by year- 2011
Figure 32: Biomarker deals with a royalty rate by year- 2010
Figure 33: Biomarker deals with a royalty rate by year- 2009
Figure 34: Summary median royalty rate by year, 2009-2014
Figure 35: Components of the typical biomarker deal structure
Figure 36: Top biomarker deals by value since 2009
Figure 37: Online partnering resources
Figure 38: Forthcoming partnering events

Published By: Current Partnering
Product Code: Current Partnering21


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