Global Market and Applications for Nanotechnology in the Life Sciences and Healthcare Industries

Report Summary

Nanotechnology is beginning to have an enormous impact on the pharmaceutical, medical devices, implants, imaging and diagnostics sectors, with annual markets of billions of dollars predicted within ten years.

According to nanoposts.com, life sciences and healthcare products enabled by nanomaterials currently represent a $1 billion plus market in 2009. First generation products on the market include nano-titania coated implants, nanoparticulate pharmaceuticals, anti-bacterial coatings for medical supplies and healing wound dressings.

The second wave of products and processes holds even greater promise, with exploitation of the properties of nanomaterials allowing for early diagnosis, detection and treatment of disease and replacement of bone and tissue for regenerative purposes. Long-term biocompatible implants and non-invasive targeted therapeutics to treat cancer are potentially achievable based on current R&D advances. Companies with product portfolios in the life sciences and healthcare markets include:

 Drug delivery: Access Pharmaceuticals (Nanoparticle Aggregate Drug Delivery Technology); Asklêpios BioPharmaceutical Inc (Biological Nano Particles (BNP™) Platform); Cornerstone Pharmaceuticals (Emulsiphan Nanoparticle Tumour Targeting Technology); Magforce Nanotechnologies (MagForce® Nanoparticles).

 Medical imaging and biosensing: AMG Pharmaceuticals (Iron nanoparticles imaging agents to aid in the diagnosis of cancer and cardiovascular disease); Nanosphere (Verigene system for molecular diagnostics).

 Anti-bacterial coatings: Bionic Surfaces (Surface-modified Silicone Rubber for medical catheters); GfE Medizintechnik GmbH (Nanoscale titanium-coated synthetic implants).
 Wound dressings: ConvaTec (Silver-containing Hydrofiber® (SCH) dressing,AQUACEL® Ag); Smith and Nephew (Acticoat nanocrystalline wound dressings).

This 213 page report provides in depth coverage of one of the most active and commercially important areas of research and application of nanotechnology.
The report includes:

• Analyses of key nanotechnologies for the life sciences and healthcare industries, and commercialization activity
• Analyses of the impact of nanotechnology on the life science and healthcare markets to 2015
• Analyses of most promising product areas in Pharmaceuticals, Drug Delivery, Medical Supplies and Devices, Implants, Biomedical Coatings, Wound Care, Diagnostics, Non-Invasive Therapies, Imaging and Tissue Engineering.
• Profiles of global companies and research centres developing commercial applications of nanotechnologies for the Life Sciences and Healthcare industries

Table Of Contents

1 INTRODUCTION 7
1.1 Nanotechnology in Life Sciences and Healthcare 7
1.2 Key applications and market opportunity to 2015 9
1.3 The global market for nanomaterials in life sciences and healthcare 11
1.3.1 Nanoscale biosensors and imaging 12
1.3.2 Nanocoatings on surfaces and implants 14
1.3.3 Nanoparticulate drug delivery 15
1.4 Key Players 19

2 KEY NANOTECHNOLOGIES 21
2.1 NANOPARTICLES 22
2.1.1 Market for nanoparticles 23
2.1.2 Key players 25
2.1.2.1 Manufacturers and End Users 25
2.1.2.2 Nanomaterials suppliers 26
2.1.2.3 Application manufacturers 27
2.2 NANOCAPSULES 28
2.2.1 Market for nanocapsules 28
2.2.2 Key players 31
2.2.2.1 Manufacturers and End Users 31
2.2.2.2 Nanomaterials suppliers 31
2.2.2.3 Application manufacturers 32
2.3 NANOPOROUS MATERIALS 33
2.3.1 Market for nanoporous materials 33
2.3.2 Key Players 36
2.3.2.1 Manufacturers and End Users 36
2.3.2.2 Nanomaterials suppliers 37
2.3.2.3 Application manufacturers 37
2.4 QUANTUM DOTS 38
2.4.1 Market for quantum dots 38
2.4.2 Key players 40
2.4.2.1 Manufacturers and End Users 40
2.4.2.2 Nanomaterials suppliers 41
2.4.2.3 Application manufacturers 41
2.5 NANOCOATINGS 42
2.5.1 Market for Nanocoatings 42
2.5.2 Key players 45
2.5.2.1 Manufacturers and End Users 45
2.5.2.2 Nanomaterials suppliers 45
2.5.2.3 Application manufacturers 46

3 TECHNOLOGY PROVIDERS 47
3.1 PHARMACEUTICALS: FORMULATION 49
3.1.1 ACROSS BARRIERS GMBH 49
3.1.2 ACTIVERY 51
3.1.3 AC-SERENDIP 54
3.1.4 COPERNICUS THERAPEUTICS, INC. 56
3.1.5 CYTOPLEX BIOSCIENCES 58
3.1.6 FERRO CORPORATION 60
3.1.7 ICEUTICA INC. 62
3.1.8 LENA NANOCEUTICS LTD. 64
3.1.9 LIQUIDIA TECHNOLOGIES 66
3.1.10 NEOWATER 69
3.1.11 STARPHARMA HOLDINGS LTD. 71
3.2 PHARMACEUTICALS: DRUG DELIVERY 72
3.2.1 ABLYNX NV 72
3.2.2 BIOCURE, INC. 75
3.2.3 BIODELIVERY SCIENCES INTERNATIONAL 77
3.2.4 CAPSULUTION NANOSCIENCE AG 79
3.2.5 CINVENTION AG 81
3.2.6 CYTIMMUNE SCIENCES 83
3.2.7 DEBIOTECH S.A. 85
3.2.8 DENDTITECH INC. 89
3.2.9 EBIOSCIENCE CORPORATION 90
3.2.10 ELAN DRUG DELIVERY 91
3.2.11 NANOBIOTIX 94
3.2.12 NANOCARRIER 96
3.2.13 NANOCYTE INC. 99
3.2.14 NANO INTERFACE TECHNOLOGY, INC. 101
3.2.15 NANOMED PHARMACEUTICALS INC. 103
3.2.16 NANOPASS TECHNOLOGIES LTD. 106
3.2.17 NANOSYS INC. 108
3.2.18 NANOTHERAPEUTICS, INC. 110
3.2.19 NOVOSOM AG 114
3.2.20 OCEAN NANOTECH, LLC. 116
3.2.21 PHARMASOL GMBH 119
3.2.22 PSIVIDIA CORP 123
3.2.23 SOL-GEL TECHNOLOGIES 125
3.2.24 SUPRATEK PHARMA 127
3.3 MEDICAL SUPPLIES AND DEVICES: IMPLANTS 129
3.3.1 AORTECH INTERNATIONAL 129
3.3.2 BERKELEY ADVANCED BIOMATERIALS INC. 131
3.3.3 INNOVATIVE BIOCERAMIX INC. 133
3.3.4 NANOCOATINGS PTY LTD. 135
3.3.5 WE SENSE LTD. 137
3.4 MEDICAL SUPPLIES AND DEVICES: COATINGS 139
3.4.1 ACRYMED, INC. 139
3.4.2 AEONCLAD BIOMEDICAL LLC 141
3.4.3 LAAM SCIENCE INC. 143
3.4.4 MIV THERAPEUTICS INC. 146
3.4.5 MOLLER MEDICAL GMBH 149
3.4.6 NANOCOPOEIA, INC. 151
3.4.7 NANO S BIOTECHNOLOGIE GMBH 153
3.4.8 NICAST LTD 155
3.4.9 SARASTRO GMBH 157
3.4.10 SURFACTIS 158
3.5 MEDICAL SUPPLIES AND DEVICES: WOUND CARE 161
3.5.1 HEIQ MATERIALS LTD. 161
3.5.2 NANOCET 163
3.6 DIAGNOSTICS AND THERAPIES 165
3.6.1 ABRAXIS BIOSCIENCES, INC. 165
3.6.2 ADURO BIOTECH 166
3.6.3 ALNIS BIOSCIENCES, INC 169
3.6.4 AMAG PHARMACEUTICALS, INC. 171
3.6.5 AMBRI BIOSENSOR TECHNOLOGY 173
3.6.6 BIOFORCE NANOSCIENCES 175
3.6.7 CHEMICELL GMBH 176
3.6.8 DIAGAM 178
3.6.9 EPOCAL INC. 179
3.6.10 FLAMEL TECHNOLOGIES 181
3.6.11 GENOVOXX GMBH 183
3.6.12 MICROMOD PARTIKELTECHNOLOGIES GMBH 184
3.6.13 NANOSPECTRA BIOSCIENCES INC. 185
3.6.14 NANOSPHERE INC. 187
3.6.15 PHARMASEQ INC. 189
3.6.16 VERIDEX LLC 191
3.7 REGENERATIVE MEDICINE 193
3.7.1 3DM INC. 193
3.7.2 EMEMBRANE INC. 195
3.7.3 ICELL THERAPEUTICS 197
3.7.4 MAGNECELL LIMITED 199

4 GLOSSARY OF TERMS 202