| TABLE OF CONTENTS |
| U.S. MARKET FOR DIAGNOSTIC ELECTROPHYSIOLOGY DEVICES, |
| ELECTRO-CARDIOGRAPHS & CARDIAC MONITORING PRODUCTS 2008 ........I |
| TABLE OF CONTENTS ..................................................................................................... II |
| LIST OF FIGURES.............................................................................................................IV |
| LIST OF CHARTS..............................................................................................................VI |
| EXECUTIVE SUMMARY ................................................................................................... 1 |
| 1.1 TOTAL MARKET FOR CARDIAC RHYTHM MANAGEMENT, ELECTROPHYSIOLOGY, AND |
| ABLATION DEVICES............................................................................................................ 1 |
| 1.2 IMPLANTABLE CARDIOVERTER DEFIBRILLATORS (ICDS)............................................ 3 |
| 1.3 PACEMAKERS................................................................................................................ 4 |
| 1.4 CARDIAC RESYNCHRONIZATION THERAPY (CRT) DEVICES........................................ 4 |
| 1.5 EXTERNAL DEFIBRILLATORS........................................................................................ 5 |
| 1.6 CARDIAC ABLATION..................................................................................................... 6 |
| 1.7 DIAGNOSTIC ELECTROPHYSIOLOGY DEVICES.............................................................. 7 |
| 1.8 ECG AND CARDIAC MONITORING PRODUCTS.............................................................. 8 |
| 1.9 LEADING COMPETITORS ............................................................................................... 9 |
| RESEARCH METHODOLOGY....................................................................................... 10 |
| 2.1 RESEARCH SCOPE ....................................................................................................... 10 |
| 2.2 IDATA’S 9-STEP METHODOLOGY ............................................................................... 10 |
| Step 1: Project Initiation & Team Selection ............................................................... 11 |
| Step 2: Prepare Data Systems and Perform Secondary Research.............................. 12 |
| Step 3: Preparation for Interviews & Survey Design ................................................. 13 |
| Step 4: Performing Primary Research........................................................................ 14 |
| Step 5: Research Analysis: Establishing Baseline Estimates ..................................... 15 |
| Step 6: Market Forecasting ........................................................................................ 16 |
| Step 7: Identify Strategic Opportunities ..................................................................... 18 |
| Step 8: Final Review and Market Release .................................................................. 19 |
| Table of Contents |
| iii |
| Step 9: Customer Feedback and Market Monitoring.................................................. 20 |
| DIAGNOSTIC ELECTROPHYSIOLOGY DEVICES ................................................... 21 |
| 3.1 INTRODUCTION ........................................................................................................... 21 |
| 3.2MARKET ANALYSIS AND FORECAST........................................................................... 23 |
| 3.2.1 EP Stimulation Devices......................................................................................... 23 |
| 3.2.2 Electrophysiology Diagnostic Catheters .............................................................. 27 |
| 3.2.3 Intracardiac Echocardiography (ICE) Diagnostic Catheters .............................. 33 |
| 3.3MARKET DRIVERS AND LIMITERS .............................................................................. 35 |
| 3.3.1 Market Drivers...................................................................................................... 35 |
| 3.3.2 Market Limiters..................................................................................................... 36 |
| 3.4 COMPETITIVE ANALYSIS ............................................................................................ 37 |
| ELECTRO-CARDIOGRAPH AND CARDIAC MONITORING PRODUCTS........... 41 |
| 4.1 INTRODUCTION ........................................................................................................... 41 |
| 4.2MARKET ANALYSIS AND FORECAST........................................................................... 43 |
| 4.2.1 Total Market for Cardiac Monitoring Products ................................................... 43 |
| 4.2.2 Resting Electro-Cardiograph (ECG) Devices Market.......................................... 45 |
| 4.2.3 Stress Testing Systems Market .............................................................................. 49 |
| 4.2.4 Holter Monitoring Systems Market....................................................................... 51 |
| 4.2.5 Event Monitoring Systems Market ........................................................................ 59 |
| 4.2.6 ECG Data Management Systems Market.............................................................. 66 |
| 4.3MARKET DRIVERS AND LIMITERS .............................................................................. 71 |
| 4.3.1 Market Drivers...................................................................................................... 71 |
| 4.3.2 Market Limiters..................................................................................................... 72 |
| 4.4 COMPETITIVE ANALYSIS ............................................................................................ 73 |
| ABBREVIATIONS.............................................................................................................. 80 |
| List of Figures |
| iv |
| LIST OF FIGURES |
| EXECUTIVE SUMMARY.................................................................................... 1 |
| RESEARCH METHODOLOGY.......................................................................... 10 |
| DIAGNOSTIC ELECTROPHYSIOLOGY DEVICES .......................................... 21 |
| Figure 10-1: Total Market for Stimulation Devices, U.S., 2004 – 2014 ................ 23 |
| Figure 10-2: Market for Analog EP Stimulation Devices, U.S., 2004 – 2014........ 25 |
| Figure 10-3: Market for Computerized EP Stimulation Devices, U.S., 2004 – |
| 2014 .............................................................................................................. 26 |
| Figure 10-4: Combined Market for Diagnostic EP Catheters, U.S., 2004 – 2014 .. 27 |
| Figure 10-5: Market for Fixed Curve Diagnostic EP Catheters, U.S., 2004 – 201429 |
| Figure 10-6: Market for Steerable Diagnostic EP Catheters, U.S., 2004 – 2014.... 31 |
| Figure 10-7: ICE Catheter Market, U.S., 2004 – 2014 ......................................... 33 |
| Figure 10-8: Drivers and Limiters for the Diagnostic Electrophysiology Market, |
| U.S., 2007 ..................................................................................................... 36 |
| Figure 10-9: Leading Competitors in the Diagnostic Electrophysiology Devices |
| Market, U.S., 2007 ........................................................................................ 39 |
| ELECTRO-CARDIOGRAPH AND CARDIAC MONITORING PRODUCTS ....... 41 |
| Figure 11-1: Total Market for Cardiac Monitoring Products, U.S., 2004 – 2014 ... 43 |
| Figure 11-2: Combined Resting ECG Market, U.S., 2004 – 2014 ......................... 45 |
| Figure 11-3: Office Based Resting ECG Market, U.S., 2004 – 2014..................... 47 |
| Figure 11-4: Hospital Based Resting ECG Market, U.S., 2004 – 2014 ................. 48 |
| Figure 11-5: Stress Testing System Market, U.S., 2004 – 2014............................ 49 |
| Figure 11-6: Total Holter Monitoring Systems Market, U.S., 2004 – 2014 ........... 51 |
| Figure 11-7: Holter Scanner Market, U.S., 2004 – 2014 ...................................... 53 |
| Figure 11-8: Holter Scanner Unit Sales by Market Segment, U.S., 2004 – 2014 ... 55 |
| Figure 11-9: Holter Monitor Market, U.S., 2004 – 2014 ...................................... 56 |
| Figure 11-10: Holter Monitor Unit Sales by Market Segment, U.S., 2004 – 2014 . 58 |
| Figure 11-11: Total Event Monitoring Systems Market, U.S., 2004 – 2014 .......... 59 |
| Figure 11-12: Event Monitoring Devices Market, U.S., 2004 – 2014 ................... 61 |
| List of Figures |
| v |
| Figure 11-13: Event Monitoring Device Sales by Type, U.S., 2004 – 2014 .......... 62 |
| Figure 11-14: Event Monitoring Receiving Station Market, U.S., 2004 – 2014..... 64 |
| Figure 11-15: ECG Data Management Systems Market, U.S., 2004 – 2014 .......... 67 |
| Figure 11-16: Office ECG Data Management Systems Market, U.S., 2004 – 2014 69 |
| Figure 11-17: Hospital ECG Data Management Systems Market, U.S., 2004 – |
| 2014 .............................................................................................................. 70 |
| Figure 11-18: Leading Competitors in the Cardiac Monitoring Market, U.S., 200776 |
| ABBREVIATIONS ............................................................................................ 80 |
| List of Charts |
| vi |
| LIST OF CHART S |
| EXECUTIVE SUMMARY.................................................................................... 1 |
| Chart 1-1: Total Cardiac Rhythm Management, Electrophysiology, and Ablation |
| Market, U.S., 2004 – 2014 ............................................................................... 1 |
| Chart 1-2: Cardiac Rhythm Management, Electrophysiology, and Ablation |
| Market by Segment, U.S., 2014 ........................................................................ 2 |
| Chart 1-3: Average Selling Price of Implantable Cardioverter Defibrillators, |
| U.S., 2004 – 2014 ............................................................................................ 3 |
| Chart 1-4: Market for Automated External Defibrillators, U.S., 2004 – 2014 ......... 5 |
| Chart 1-5: Total Market for Cardiac Ablation Catheters, U.S., 2004 – 2014 ........... 6 |
| Chart 1-6: Unit Sales of Diagnostic Electrophysiology Catheters, U.S., 2004 – |
| 2014 ................................................................................................................ 7 |
| Chart 1-7: Total Market for Cardiac Monitoring Products, U.S., 2004 – 2014 ........ 8 |
| Chart 1-8: Leading Competitors in the Cardiac Rhythm Management, |
| Electrophysiology, and Ablation Market, U.S., 2007 ........................................ 9 |
| RESEARCH METHODOLOGY.......................................................................... 10 |
| DIAGNOSTIC ELECTROPHYSIOLOGY DEVICES .......................................... 21 |
| Chart 10-1: Total Market for Stimulation Devices, U.S., 2004 – 2014 ................. 24 |
| Chart 10-2: Combined Market for Diagnostic EP Catheters, U.S., 2004 – 2014 .... 28 |
| Chart 10-3: Market for Fixed Curve Diagnostic EP Catheters, U.S., 2004 – 2014. 30 |
| Chart 10-4: Market for Steerable Diagnostic EP Catheters, U.S., 2004 – 2014 ..... 32 |
| Chart 10-5: ICE Catheter Market, U.S., 2004 – 2014........................................... 34 |
| Chart 10-6: Leading Competitors in the Diagnostic Electrophysiology Devices |
| Market, U.S., 2007 ........................................................................................ 40 |
| ELECTRO-CARDIOGRAPH AND CARDIAC MONITORING PRODUCTS ....... 41 |
| Chart 11-1: Total Market for Cardiac Monitoring Products, U.S., 2004 – 2014 .... 44 |
| Chart 11-2: Combined Resting ECG Market, U.S. 2004 – 2014 ........................... 46 |
| Chart 11-3: Stress Testing System Market, U.S., 2004 – 2014 ............................. 50 |
| List of Charts |
| vii |
| Chart 11-4: Total Holter Monitoring Systems Market Revenue by Segment, U.S., |
| 2004 – 2014................................................................................................... 52 |
| Chart 11-5: Holter Scanner Market, U.S., 2004 – 2014 ........................................ 54 |
| Chart 11-6: Holter Monitor Market, U.S., 2004 – 2014........................................ 57 |
| Chart 11-7: Event Monitoring Devices Market, U.S., 2004 – 2014....................... 61 |
| Chart 11-8: Event Monitoring Device Sales by Type, U.S., 2004 – 2014.............. 63 |
| Chart 11-9: Event Monitoring Receiving Station Market, U.S., 2004 – 2014 ........ 65 |
| Chart 11-10: ECG Data Management Systems Market, U.S., 2004 – 2014............ 68 |
| Chart 11-11: Leading Competitors in the Resting ECG Market, U.S., 2007 .......... 77 |
| Chart 11-12: Leading Competitors in the Stress Testing ECG Market, U.S., 2007 77 |
| Chart 11-13: Leading Competitors in the Holter Monitoring Market, U.S., 2007 .. 78 |
| Chart 11-14: Leading Competitors in the Event Monitoring Market, U.S., 2007 ... 78 |
| Chart 11-15: Leading Competitors in the ECG Data Management System Market, |
| U.S., 2007 ..................................................................................................... 79 |
| Chart 11-16: Leading Competitors in the Total Cardiac Monitoring Market, U.S., |
| 2007 .............................................................................................................. 79 |