TABLE OF CONTENTS
TABLE OF CONTENTS.......................................................................................................I
LIST OF FIGURES...............................................................................................................V
LIST OF CHARTS............................................................................................................ VII
RESEARCH METHODOLOGY......................................................................................... 8
1.1 RESEARCH SCOPE ......................................................................................................... 8
1.2 IDATA’S 9-STEP METHODOLOGY ................................................................................. 8
Step 1: Project Initiation & Team Selection ................................................................. 9
Step 2: Prepare Data Systems and Perform Secondary Research.............................. 10
Step 3: Preparation for Interviews & Questionnaire Design ..................................... 11
Step 4: Performing Primary Research........................................................................ 12
Step 5: Research Analysis: Establishing Baseline Estimates ..................................... 14
Step 6: Market Forecast and Analysis ........................................................................ 14
Step 7: Identify Strategic Opportunities ..................................................................... 16
Step 8: Final Review and Market Release .................................................................. 17
Step 9: Customer Feedback and Market Monitoring.................................................. 18
EUROPEAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET............................................................................................. 19
2.1 APPLICATIONS OF DENTAL BONE GRAFT SUBSTITUTES ............................................ 19
2.1.1 Dental Implant Procedures................................................................................... 20
2.1.2 Periodontal Procedures........................................................................................ 20
2.2 TYPES OF DENTAL BONE GRAFT SUBSTITUTES.......................................................... 21
2.2.1 Autografts.............................................................................................................. 21
2.2.2 Allografts .............................................................................................................. 21
2.2.3 De-Mineralized Bone Matrix (DBM) Allografts................................................... 22
2.2.4 Xenografts............................................................................................................. 23
2.2.5 Synthetics .............................................................................................................. 23
Table of Contents
iii
2.3 TISSUE ENGINEERING PRODUCTS............................................................................... 24
2.4 DENTAL MEMBRANES ................................................................................................ 25
2.5MARKET PENETRATION AND END USERS................................................................... 26
2.6 CURRENCY EXCHANGE RATES ................................................................................... 26
COUNTRY PROFILES...................................................................................................... 29
3.1 INTRODUCTION ........................................................................................................... 29
3.1.1 Population............................................................................................................. 29
3.1.2 GDP per Capita .................................................................................................... 31
3.1.3 Bone Graft Volume Used (cc) Per 10,000 Inhabitants ......................................... 33
3.1.4 Price Index............................................................................................................ 35
3.2 ITALY .......................................................................................................................... 37
3.3 EUROPEAN TOOTH LOSS STATISTICS ......................................................................... 38
3.4 POPULATION PER DENTIST BY COUNTRY ................................................................... 40
ITALIAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER BIOMATERIALS
MARKET............................................................................................................................ 43
4.1 INTRODUCTION ........................................................................................................... 43
4.1.1 Dental Bone Grafting Procedures ........................................................................ 44
4.2 DENTAL BONE GRAFT SUBSTITUTE MARKET ANALYSIS AND FORECAST ................. 46
4.2.1 Total Market for Italian BGS Materials ............................................................... 46
4.2.2 Material Volume Sold by BGS Type ..................................................................... 49
4.2.3 Autograft Market................................................................................................... 52
4.2.4 Allograft Market ................................................................................................... 53
4.2.4.1 Mineralized Allografts .....................................................................................53
4.2.4.2 De-Mineralized Allografts (DBMs) .................................................................54
4.2.5 Xenograft Market.................................................................................................. 55
4.2.6 Synthetic Biomaterials Market.............................................................................. 56
4.3MARKET DRIVERS AND LIMITERS .............................................................................. 57
4.3.1 Market Drivers...................................................................................................... 57
4.3.2 Market Limiters..................................................................................................... 57
4.4 COMPETITIVE ANALYSIS ............................................................................................ 60
4.5 DENTAL MEMBRANES MARKET ................................................................................. 63
4.5.1 Market Analysis and Forecast .............................................................................. 63
Table of Contents
iv
4.5.2 Market Drivers...................................................................................................... 66
4.5.3 Market Limiters..................................................................................................... 66
4.5.4 Competitive Analysis............................................................................................. 68
ABBREVIATIONS.............................................................................................................. 72
List of Figures
v
LIST OF FIGURES
RESEARCH METHODOLOGY............................................................................ 8
EUROPEAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET.......................................................................... 19
Figure 3-1: Exchange Rates for the Euro (€), 2008.............................................. 27
Figure 3-2: Exchange Rates Between European Currencies, 2008 ....................... 28
COUNTRY PROFILES ...................................................................................... 29
Figure 4-1: European Country Populations, 2008 ............................................... 29
Figure 4-2: European GDP per Capita, 2008 (US$) ............................................ 31
Figure 4-3: Dental BGS Used (cc) Per 10,000 Inhabitants, Europe, 2008 ............ 33
Figure 4-4: Price Indices for Dental Bone Graft Substitutes, 2008 ...................... 35
Figure 4-5: Population per Dentist by Country, 2008........................................... 41
Figure 4-6: Legend for Chart 4-18: Population per Dentist by Country .............. 41
ITALIAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET.......................................................................... 43
Figure 8-1: BGS Procedures and Penetration Rates, Italy, 2005 – 2015................ 45
Figure 8-2: Total Market for BGS Materials, Italy, 2005 – 2015 (€) .................... 46
Figure 8-3: Total Market for BGS Materials, Italy, 2005 – 2015 (US$)................ 47
Figure 8-4: Material Volume Sold by BGS Type, Italy, 2005 – 2015 ................... 49
Figure 8-5: Potential Dental Autograft Market, Italy, 2005 – 2015 (€) ................. 52
Figure 8-6: Dental Mineralized Allograft Market, Italy, 2005 – 2015 (€) ............. 53
Figure 8-7: Dental De-Mineralized Bone Matrix (DBM) Market, Italy, 2005 –
2015 (€) ........................................................................................................ 54
Figure 8-8: Dental Xenograft Market, Italy, 2005 – 2015 (€) ............................... 55
Figure 8-9: Dental Synthetic Bone Graft Materials Market, Italy, 2005 – 2015 (€)56
Figure 8-10: Drivers and Limiters of the Italian Market for Dental Bone Graft
Substitutes, 2008 ........................................................................................... 59
Figure 8-11: Leading Competitors in the Dental BGS Market, Italy, 2008............ 61
Figure 8-12: Market for Dental Membranes, Italy, 2005 – 2015 (€) ..................... 63
List of Figures
vi
Figure 8-13: Market for Dental Membranes, Italy, 2005 – 2015 (US$)................. 64
Figure 8-14: Drivers and Limiters of the Italian Dental Membrane Market, 2008 67
Figure 8-15: Leading Competitors in the Dental Membrane Market, Italy, 2008... 70
ABBREVIATIONS ............................................................................................ 72
List of Charts
vii
LIST OF CHART S
RESEARCH METHODOLOGY............................................................................ 8
EUROPEAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET.......................................................................... 19
COUNTRY PROFILES ...................................................................................... 29
Chart 4-1: European Country Populations, 2008................................................. 30
Chart 4-2: European GDP per Capita, 2008 (US$).............................................. 32
Chart 4-3: Dental BGS Used (cc) Per 10,000 Inhabitants, Europe, 2008.............. 34
Chart 4-4: Price Indices for Dental Bone Graft Substitutes, 2008 ....................... 36
Chart 4-8: Italian Price Index, BGS Used per Capita, GDP per Capita, and
Population, 2008 (US$).................................................................................. 37
Chart 4-17: Edentulism Rates Among Those Between 65 and 74 Years of Age,
Europe, 2008 ................................................................................................. 39
Chart 4-18: Population per Dentist by Country................................................... 42
ITALIAN DENTAL BONE GRAFT SUBSTITUTES AND OTHER
BIOMATERIALS MARKET.......................................................................... 43
Chart 8-1: Total Market for BGS Materials, Italy, 2005 – 2015 (€) ...................... 48
Chart 8-2: Material Volume Sold by BGS Type, Italy, 2005 – 2015 ..................... 50
Chart 8-3: Material Volume Sold by BGS Type, Italy, 2008 ............................... 51
Chart 8-4: Leading Competitors in the Dental BGS Market, Italy, 2008 ............... 62
Chart 8-5: Market for Dental Membranes, Italy, 2005 – 2015 (€)......................... 65
Chart 8-6: Leading Competitors in the Dental Membrane Market, Italy, 2008 ...... 71
ABBREVIATIONS ............................................................................................ 72