European Markets for Dental Bone Graft Substitutes and Other Biomaterials 2009

In 2008, the combined European market for dental bone graft substitutes and other biomaterials increased by 12.9% over 2007. The European market includes Austria, Benelux, France, Germany, Israel, Italy, Poland, Portugal, Scandinavia, Spain, Switzerland and the United Kingdom. In 2008, the fastest growing bone graft substitute type was DBM or de-mineralized bone matric allografts. The dental bone graft substitute market is segmented by type into both mineralized and DBM allografts, xenografts and synthetics. The potential market for allografts is also explored

TABLE OF CONTENTS
EUROPEAN MARKETS FOR DRUG-ELUTING AND BARE METAL STENTS 2009
(15 COUNTRIES)...................................................................................................................I
IDATA_EUDES09_RPT........................................................................................................I
TABLE OF CONTENTS..................................................................................................... II
LIST OF FIGURES...............................................................................................................V
LIST OF CHARTS............................................................................................................ VII
RESEARCH METHODOLOGY......................................................................................... 9
1.1 RESEARCH SCOPE ......................................................................................................... 9
1.2 IDATA’S 9-STEP METHODOLOGY ................................................................................. 9
Step 1: Project Initiation & Team Selection ............................................................... 10
Step 2: Prepare Data Systems and Perform Secondary Research.............................. 11
Step 3: Preparation for Interviews & Questionnaire Design ..................................... 12
Step 4: Performing Primary Research........................................................................ 13
Step 5: Research Analysis: Establishing Baseline Estimates ..................................... 15
Step 6: Market Forecast and Analysis ........................................................................ 15
Step 7: Identify Strategic Opportunities ..................................................................... 17
Step 8: Final Review and Market Release .................................................................. 18
Step 9: Customer Feedback and Market Monitoring.................................................. 19
EUROPEAN MARKET FOR INTERVENTIONAL CARDIOLOGY DEVICES....... 20
2.1 INTRODUCTION ........................................................................................................... 20
2.2 CURRENCY EXCHANGE RATES ................................................................................... 21
2.3 EFFECTS OF THE ECONOMIC CRISIS............................................................................ 22
COUNTRY PROFILES...................................................................................................... 23
3.1 INTRODUCTION ........................................................................................................... 23
Table of Contents
   iii
3.1.1 Population............................................................................................................. 23
3.1.2 GDP per Capita .................................................................................................... 23
3.1.3 PCI and DES Penetration Rates ........................................................................... 23
3.1.4 Price Index............................................................................................................ 24
3.2 GERMANY................................................................................................................... 25
3.3 FRANCE....................................................................................................................... 26
3.4 UNITED KINGDOM ...................................................................................................... 27
3.5 ITALY .......................................................................................................................... 28
3.6 SPAIN .......................................................................................................................... 29
3.7 BENELUX .................................................................................................................... 30
3.8 SCANDINAVIA ............................................................................................................. 31
3.9 PORTUGAL .................................................................................................................. 32
3.10 AUSTRIA ................................................................................................................... 33
3.11 SWITZERLAND........................................................................................................... 34
BARE-METAL AND DRUG-ELUTING STENTS.......................................................... 35
4.1 INTRODUCTION ........................................................................................................... 35
4.2 OVERVIEW OF THE MARKET....................................................................................... 37
4.2.1 Total Coronary Stent Market................................................................................ 37
4.2.2 Bare-Metal versus Drug-Eluting Stents................................................................ 42
4.3 MARKET ANALYSIS AND FORECAST .......................................................................... 45
4.3.1 Bare-Metal Stent Market ...................................................................................... 45
4.3.1.1 Market Analysis and Forecast .........................................................................45
4.3.1.2 Bare-Metal Stent Market Drivers ....................................................................50
4.3.1.3 Bare-Metal Stent Market Limiters ...................................................................50
4.3.1.4 Bare-Metal Stent Competitive Analysis ...........................................................52
4.3.2 Drug-Eluting Stent Market ................................................................................... 55
4.3.2.1 Market Analysis and Forecast .........................................................................55
4.3.2.2 Drug-Eluting Stent Market Drivers .................................................................59
4.3.2.3 Drug-Eluting Stent Market Limiters ................................................................59
4.3.2.4 Drug-Eluting Stent Competitive Analysis ........................................................62
4.3.3 Stents in Development........................................................................................... 66
4.3.3.1 Bioabsorbable Stents .......................................................................................67
4.3.3.2 Bifurcated Stents..............................................................................................70
Table of Contents
   iv
ABBREVIATIONS.............................................................................................................. 73
List of Figures
   v
LIST OF FIGURES
RESEARCH METHODOLOGY............................................................................ 9
EUROPEAN MARKET FOR INTERVENTIONAL CARDIOLOGY DEVICES.... 20
Figure 2-1: Exchange Rates for the Euro (€), 2008.............................................. 21
COUNTRY PROFILES ...................................................................................... 23
Figure 3-1: Country Indicators, 2008 .................................................................. 24
BARE-METAL AND DRUG-ELUTING STENTS............................................... 35
Figure 4-1: Market for Coronary Stents by Type, Europe, 2005 – 2015 (€) .......... 38
Figure 4-2: Market for Coronary Stents by Type, Europe, 2005 – 2015 (US$)...... 38
Figure 4-3: Market for Coronary Stents by Country, Europe, 2005 – 2015 (€)...... 40
Figure 4-4: Market for Coronary Stents by Country, Europe, 2005 – 2015 (US$) . 41
Figure 4-5: Penetration Rate for Coronary Stents by Type, Units Sold, Europe,
2005 – 2015................................................................................................... 42
Figure 4-6: DES Penetration by Country, Europe, 2005 – 2015 ........................... 43
Figure 4-7: Market for Bare-Metal Stents by Country, Europe, 2005 – 2015 (€)... 47
Figure 4-8: Market for Bare-Metal Stents by Country, Europe, 2005 – 2015 (US$)48
Figure 4-9: Market Drivers and Limiters, Market for Bare-Metal Stents, Europe,
2008 .............................................................................................................. 51
Figure 4-10: Leading Competitors, Market for Bare-Metal Stents, Europe, 2008.. 53
Figure 4-11: Market for Drug-Eluting Stents by Country, Europe, 2005 – 2015 (€)56
Figure 4-12: Market for Drug-Eluting Stents by Country, Europe, 2005 – 2015
(US$) ............................................................................................................ 57
Figure 4-13: Market Drivers and Limiters, Market for Drug-Eluting Stents,
Europe, 2008 ................................................................................................. 61
Figure 4-14: Leading Competitors, Market for Drug-Eluting Stents, Europe, 200864
Figure 4-15: Coronary Stent Platforms in Development, 2008 ............................. 66
Figure 4-16: Potential Market for Bioabsorbable Stents, Europe, 2010 – 2015 (€) 68
Figure 4-17: Potential Market for Bioabsorbable Stents, Europe, 2010 – 2015
(US$) ............................................................................................................ 68
List of Figures
   vi
Figure 4-18: Potential Market for Bifurcated Stents, Europe, 2010 – 2015 (€) ..... 71
Figure 4-19: Potential Market for Bifurcated Stents, Europe, 2010 – 2015 (US$) . 71
ABBREVIATIONS ............................................................................................ 73
List of Charts
   vii
LIST OF CHART S
RESEARCH METHODOLOGY............................................................................ 9
EUROPEAN MARKET FOR INTERVENTIONAL CARDIOLOGY DEVICES.... 20
COUNTRY PROFILES ...................................................................................... 23
Chart 3-1: German Price Index, DES Penetration, Population, GDP per Capita,
and PCI Penetration Rate, 2008 ...................................................................... 25
Chart 3-2: French Price Index, DES Penetration, Population, GDP per Capita,
and PCI Penetration Rate, 2008 ...................................................................... 26
Chart 3-3: The U.K. Price Index, DES Penetration, Population, GDP per Capita,
and PCI Penetration Rate, 2008 ...................................................................... 27
Chart 3-4: Italian Price Index, DES Penetration, Population, GDP per Capita, and
PCI Penetration Rate, 2008 ............................................................................ 28
Chart 3-5: Spanish Price Index, DES Penetration, Population, GDP per Capita,
and PCI Penetration Rate, 2008 ...................................................................... 29
Chart 3-6: Beneluxian Price Index, DES Penetration, Population, GDP per
Capita, and PCI Penetration Rate, 2008 .......................................................... 30
Chart 3-7: Scandinavian Price Index, DES Penetration, Population, GDP per
Capita, and PCI Penetration Rate, 2008 .......................................................... 31
Chart 3-8: Portuguese Price Index, DES Penetration, Population, GDP per
Capita, and PCI Penetration Rate, 2008 .......................................................... 32
Chart 3-9: Austrian Price Index, DES Penetration, Population, GDP per Capita,
and PCI Penetration Rate, 2008 ...................................................................... 33
Chart 3-10: Swiss Price Index, DES Penetration, Population, GDP per Capita,
and PCI Penetration Rate, 2008 ...................................................................... 34
BARE-METAL AND DRUG-ELUTING STENTS............................................... 35
Chart 4-1: Market for Coronary Stents by Type, Europe, 2005 – 2015 (€)............ 39
Chart 4-2: Penetration Rate for Coronary Stents by Type, Units Sold, Europe,
2005 – 2015................................................................................................... 44
Chart 4-3: Market for Bare-Metal Stents, Europe, 2005 – 2015 (€) ...................... 49
List of Charts
   viii
Chart 4-4: Leading Competitors, Market for Bare-Metal Stents, Europe, 2008 ..... 54
Chart 4-5: Market for Drug-Eluting Stents, Europe, 2005 – 2015 (€) ................... 58
Chart 4-6: Leading Competitors, Market for Drug-Eluting Stents, Europe, 2008 .. 65
Chart 4-7: Penetration Rate for Bioabsorbable Stents, Europe, 2010 – 2015......... 69
Chart 4-8: Penetration Rate for Bifurcated Stents, Europe, 2010 – 2015 .............. 72
ABBREVIATIONS ............................................................................................ 73