Vaccines 2009 World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry

Published: May 2009
No. of Pages: 150
  

The global market for human vaccines has experienced strong growth through 2008 and this is expected to continue through the forecast period. Growth will be fueled by new product introductions and rising usage in all regions.

This report, Vaccines 2009: Key Players, and Critical Trends in a Fast-Changing Industry), examines the market for vaccines used in humans to previous various types of disease. Sales estimates for each market segment represent global revenues and are expressed in current dollars. Estimates are provided for the historic 2008 period and forecasts are provided through 2013.

Since the last edition of this report:
  • Vaccine makers are now advertising directly to the public with growing DTC budgets. The report identifies the possible market impact of this new trend.

  • The economy has impacted vaccine sales with more people unable to make required out of pocket payments for vaccination.

  • New categories of vaccines, such as allergy vaccines, are becoming more prominent, and have been included in our forecasts.

  • Several major new products, including Wyeth's Prevnar 13, are on the horizon. The market impact of new products is discussed.

  • Two major mergers - Pfizer/Wyeth and Merck/Schering-Plough, will impact the industry and this is considered in our market analysis.
Few areas of pharmaceuticals have seen the fast-moving developments in the marketplace that the vaccine market has in 2008. Since Kalorama Information last updated Kalorama Information's The World Market for Vaccines last year, new products and better than expected profits have transformed the vaccine marketplace. Continued sales of influenza vaccines and cervical cancer vaccines have provided a foundation for growth in the adult market. The competitive dynamics have changed with mergers, and many new products are on the way.

Kalorama Information's exhaustive research and analysis built from interviews with key decision makers in the market includes the following:
  • Review of Products in the Market
  • Current World Market Size for Pediatric and Adult Vaccines
  • Segmented Revenues and Forecasts to 2013 by Category
  • Over 45 Charts and Tables To Make Information Accessible
  • Discussion of The Current Economy and Vaccines, Immunization Refusal, Swine/Avian Flu and Other Pandemics, Delivery Sys and other Trends in the Vaccine Market
  • Important Vaccines and Immunization Schedules and Statistics
  • Profiles of 15 Key Vaccine Companies
  • Thorough Review of the Vaccine Pipeline and Possible Impact of New Products
Who are the main players in the vaccine market? What opportunities are available for pharmaceutical companies or investors from this market? What are the potential challenges vaccine competitors must deal with? What will be the impact of the first successful cancer product? What is the significance of at least one major acquisition to affect this industry? These questions and more are tackled in this report.

Current revenues and revenue forecasts to 2013 are included for the following pediatric vaccine categories:
  • DTaP & DTP Vaccines
  • Hep Vaccines
  • HiB Vaccines
  • MMR Vaccines
  • Combination Vaccines
  • Pneumococcal Vaccines
  • Polio Vaccines
  • Varicella Vaccines
  • Other Pediatric Vaccines
As well as Revenues and Forecasts to 2012 for the following adult vaccine categories:
  • Influenza Vaccines
  • Hepatitis Vaccines
  • Pneumococcal Vaccines
  • Travel, DT and other Adult Vaccines
  • Cervical Cancer
This is a rapidly changing marketplace and knowledge of the R&D pipeline is essential to truly understand what is happening in vaccines. Vaccines in development are discussed in this report, including vaccines for the following conditions:
  • Enterotoxigenic Escherichia coli
  • Parainfluenza Virus Type 3
  • Pneumococcal Vaccines
  • Respiratory Syncytial Virus
  • Cancers
  • Cholera
  • HIV/AIDS
  • Helicobacter Pylori
  • Malaria
  • Rabies
  • Tuberculosis
  • West Nile Virus
This Kalorama Information report was created with a primary research effort. Historical information for this report was gathered from a wide variety of published sources including company reports and filings, government documents, legal filings, trade journals, newspapers and business press, analysts’ reports and other sources. Interviews with company representatives and other experts were conducted to capture the perspectives from industry participants’ point of view and assess trends, and form the basis of the forecasting and competitive analysis.

Vaccines 2009 World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry

CHAPTER ONE: EXECUTIVE SUMMARY
THE GLOBAL VACCINES INDUSTRY
Scope And Methodology
Overview
Pediatric Preventative Vaccines
The Market
Adult Preventative Vaccines
The Market
Total Market
Issues and Trends

CHAPTER TWO: INTRODUCTION TO VACCINES
A Brief History: The Development of Vaccines
The Immune Response
Mechanism of Action
Types of Vaccines
Attenuated (Weakened) Live Viruses
Killed (Inactivated) Viruses
Toxoid Vaccines
Genetically Engineered/Modified Vaccines
Subunit Vaccines
Conjugate Vaccines
DNA Vaccination
Vaccine Approval Process

CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES
Introduction
Childhood Immunization in the United States
Childhood Immunization Rates
Challenges to the Vaccine Delivery System
Recommended Childhood Immunization Schedule
State Immunization Recommendations
Pediatric Vaccine Products
BCG
Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio
Diphtheria
Pertussis
Tetanus
Hepatitis B
Poliomyelitis
Enterotoxigenic Escherichia coli
Haemophilus Influenzae Type B
Hepatitis A
Measles, Mumps and Rubella
Measles
Mumps
Rubella
Meningococcal Disease
Parainfluenza Virus Type 3
Pneumococcal Conjugate
Respiratory Syncytial Virus
Rotavirus
Varicella
Pediatric Vaccines in Development
Global Initiatives for Vaccine Research
Cost of Vaccines in the United States
The World Market for Pediatric Preventive Vaccines
Total Market Size and Forecast
Hepatitis Vaccine Market
Market Analysis
Leading Products and Competitors
Haemophilus Influenzae Type B Vaccine Market
Market Analysis
Leading Products and Competitors
Measles, Mumps and Rubella Vaccines
Market Analysis
Combination Vaccines Market
Market Analysis
Leading Products and Competitors
Pneumococcal Vaccine
Leading Products and Competitors
Poliovirus Vaccine
Market Analysis
Leading Products and Competitors
Varicella Vaccines
Market Analysis
Leading Products and Competitors
Other Vaccines Market
Market Analysis
Leading Products and Competitors

CHAPTER FOUR: ADULT PREVENTIVE VACCINES
Introduction
Adult Vaccine-Preventable Diseases: Facts and Figures
Global Virological Surveillance Program
Recommendations for Adult Immunizations
WHO International Health Regulations
Adult Vaccine Products
Allergy
BCG
Cancer
Cervical Cancer
Cholera
Diphtheria-Tetanus
Helicobacter Pylori
Hepatitis
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
Herpesvirus
HIV/AIDS
Influenza
Japanese Encephalitis
Leishmaniasis
Malaria
Pneumococcal Disease
Rabies
Shingles
Tuberculosis
Typhoid Fever
West Nile Virus
Yellow Fever
Adult Vaccines in Development
Global Initiatives for Vaccine Research
The World Market for Adult Preventive Vaccines
Total Market Size and Forecast
Cervical Cancer Market
Market Analysis
Leading Products and Competitors
Hepatitis Market
Market Analysis
Leading Products and Competitors
Influenza Vaccine Market
Market Analysis
Leading Products and Competitors
Market Analysis
Leading Products and Competitors
Travel, DT, and Miscellaneous Vaccine Market
Market Analysis
Leading Products and Competitors

CHAPTER FIVE: VACCINES MARKET SUMMARY
Trends Driving the Vaccines Market
Market Size and Forecast
Vaccine Market Competitors
Pediatric Vaccines
Major Manufacturer’s Market Share
Adult Vaccines
Major Manufacturer’s Market Share

CHAPTER SIX: ISSUES AND TRENDS
Vaccine Safety
Refusal to Immunize
Post-Licensure Surveillance
Vaccine Adverse Event Reporting System
The Vaccine Safety Datalink Project
Phase IV studies
The Vaccine Injury Compensation Program
World Health Organization
Other Initiatives
The Future of Vaccine Safety
Vaccine Shortages
Preventing Shortages in the Developed Countries
Financial incentives
Equitable pricing
Vaccine stockpiles
Preventing Shortages in Developing Nations
Vaccine bonds
Economic Effects
Industrialized Nations
Developing Nations
Preventing Pandemics
U.S. National Vaccine Plan
Vaccines and Bioterrorism
Overview
Project Bioshield Act of 2004
National Bio and Agro-Defense Facility
Vaccine Treatment and Evaluation Units
Anthrax
Smallpox
Plague
Botulism
Tularemia
Viral Hemorrhagic Fevers
DNA Vaccination
Innovations in Vaccine Delivery Systems
Edible Vaccines
Mucosal Delivery
Intranasal Delivery
Vaccine Patches
DTC Advertising

CHAPTER SEVEN: COMPANY PROFILES
Acambis plc
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
AlphaVax, Inc.
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Bavarian Nordic A/S
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Baxter Healthcare
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Celldex Therapeutics
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Crucell
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Emergent Biosolutions
History and Lines of Business
Strategic Acquisition and Alliance
Vaccine Products
Financial
GlaxoSmithKline
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Medimmune
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Merck & Co. Inc
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Nabi Biopharmaceuticals
History and Lines of Business
Strategic Alliance
Vaccine Products
Financial Information
Novartis
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
History and Lines of Business
Strategic alliances
Vaccine products
Financial Information
Pharmexa
History and Lines of Business
Strategic alliances
Vaccine Products
Financial Information
Sanofi Pasteur
History and Lines of Business
Strategic Alliances
Vaccine Products
Financial Information
Wyeth
History and Lines of Business
Vaccine Products
Financial Information

APPENDIX: COMPANY DIRECTORY LIST OF EXHBITS

CHAPTER ONE: EXECUTIVE SUMMARY
Figure 1-1: World Market for Pediatric Vaccines 2004-2013
Figure 1-2: World Market for Adult Vaccines 2004-2013

CHAPTER TWO: INTRODUCTION TO VACCINES
Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2008
Table 2-2: Vaccine-Preventable Diseases, April 2009
Table 2-3: VAERS Table of Reportable Events Following Vaccination
Table 2-3 (cont.): VAERS Table of Reportable Events Following Vaccination

CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES
Table 3-1: Global Immunization Rates by Vaccine Type 2007
Table 3-2: Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by Disease 2000-2007
Table 3-3: U.S. Recommended Immunization Schedule for Children Ages 0 Through 6 Years, 2009
Table 3-4: U.S. Recommended Immunization Schedule for Adolescents Ages 7 to 18 Years, 2009
Table 3-5: Selected Pediatric Vaccines in Development, April 2009
Table 3-6: World Market for Pediatric Vaccines by Type (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others) 2004-2013 Revenues (in millions)
Figure 3-1: Market Share of Pediatric Vaccines by Type 2008 (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)
Figure 3-2: Market Share of Pediatric Vaccines, by Type 2013 (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)
Table 3-7: World Pediatric Hepatitis Vaccine Market 2004-2013
Table 3-8: World Hib Vaccine Market, 2004-2013
Table 3-9: World MMR Vaccines Market 2004-2013
Table 3-10: World Combination Vaccines Market 2004-2013
Table 3-11: World Pediatric Pneumococcal Vaccine Market 2004-2013
Table 3-12: World Poliovirus Vaccine Market 2004-2013
Table 3-13: World Varicella Vaccine Market 2004-2013
Table 3-14: Other Vaccines Market 2004-2013

CHAPTER FOUR: ADULT PREVENTIVE VACCINES
Table 4-1: Universal Adult Immunization Schedule 2009
Table 4-2: Adult Immunization Schedule for Populations with Special Medical Conditions, 2008
Table 4-3: Initiatives to Require HPV Vaccination by U.S. State, 2009
Table 4-4: WHO Pandemic Classification Schedule
Table 4-5: Selected Adult Preventive Vaccines in Development, 2009
Table 4-6: World Market for Adult Preventive Vaccines by Type (Hepatitis, Influenza, Pneumococcal, Travel/DT/Misc.), 2004-2013 Revenues (in millions)
Figure 4-1: Market Share of Adult Vaccines, by Type, 2009
Figure 4-2: Market Share of Adult Vaccines, by Type, 2013
Table 4-7: World Cervical CancerVaccine Market 2004-2013
Table 4-8: World Hepatitis Vaccine Market 2004-2014
Table 4-9: World Influenza Vaccine Market 2004-2013
Table 4-10: CDC Goal to Double Flu Immunization by 2010 Group and Estimated Immunization Rate (2000 vs 2010)
Table 4-11: 2007 Estimated Population by Region and Selected Age Group (in millions)
Table 4-12: World Pneumococcal Vaccine Market 2004-2013
Table 4-13: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market 2004-2013

CHAPTER FIVE: VACCINES MARKET SUMMARY
Figure 5-1: Sales Growth of Vaccines vs. Pharmaceuticals 2004-2013
Figure 5-2: World Market for Vaccines by Type 2004-2013
Table 5-1: The World Vaccines Market by Vaccine Type 2004-2013 Revenues (in millions)
Figure 5-3: World Market for Vaccines Share by Type, 2004, 2008 and 2013
Table 5-2: Major Manufacturers’ Shares of the World Vaccine Market, 2008
Figure 5-3: 2008 World Vaccines Market Share, by Leading Competitors
Table 5-3: Major Manufacturer’s Shares of the World Pediatric Vaccine Market 2008
Figure 5-5: Market Share of Pediatric Vaccines Market, 2008
Table 5-4: Major Manufacturer’s Shares of the World Adult Vaccine Market 2008
Figure 5-6: Market Share of Adult Vaccines Market 2008

CHAPTER SIX: ISSUES AND TRENDS
Table 7-1: Selected Companies/Laboratories Developing Biodefense Vaccines
Published By: Kalorama Information
Product Code: Kalorama Information31



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