Global Antithrombin III Market: US, Europe, Japan

The growing cost-containment pressures in major industrialized nations and continued technological advances will radically change coagulation testing practice during the next ten years. New specific and sensitive markers of hemostasis will be increasingly used on automated instrumentation. Coagulation testing in general, and AT III testing specifically, will become more standardized, offering opportunities for quality control products and services. Moreover, the continuing contraction of the hospital system and technological advances will facilitate decentralization of the AT III testing closer to the patient, creating additional opportunities and challenges for suppliers.

This report presents a detailed analysis of the AT III testing market in the US, Europe (France, Germany, Italy, Spain, UK) and Japan, including clinical significance and current laboratory practice, as well as 5- and 10-year test volume forecasts by country and market segment.

The report examines market applications of chromogenic substrates, monoclonal antibodies, immunoassays, IT, DNA probes, biochips/microarrays, and other technologies; reviews features and operating characteristics of automated analyzers; profiles leading suppliers and recent market entrants developing innovative technologies and products; and identifies alternative market penetration strategies and entry barriers/risks.

Table of Contents

I. Introduction

II. Worldwide Market and Technology Overview

A. Introduction

B. Antithrombin III: Clinical Significance: Clinical Significance and Current Laboratory Procedures

C. Instrumentation Review

Introduction
Benk Hemolab
Benk TRT Thrombotimer
Bio/Data MCA 310
Bio/Data MCA 210
Bio/Data PAP-4C D/4D/4C
Cardiovascular Diagnostics COAG
Diagnostica Stago STA Compact
Diagnostica Stago STA-R
Diagnostica Stago Star 4/8
Helena Laboratories Cascade 480
Helena Laboratories Cascade M
Helena Laboratories PACKS-4
Helena THOR
Instrumentation Laboratory ACL 100 and 1000 series
Instrumentation Laboratory ACL6000
Instrumentation Laboratory ACL7000
Instrumentation Laboratory ACL9000
Instrumentation Laboratory Electra 1000C
Instrumentation Laboratory Electra 1400C
Instrumentation Laboratory Electra 1600/C
Instrumentation Laboratory Electra 1800C
Instrumentation Laboratory Futura
ITC Hemochron 8000
Roche Diagnostics CoaguChek
Siemens BCS
Siemens BCT
Siemens BF II/Fibrintimer Series
Sysmex CA-50
Sysmex CA-500
Sysmex CA-1500
Sysmex CA-5000/CA-1000
Sysmex CA-6000
Sysmex CA-7000
Teco Coatron II/Jr./AccuStasis 5000
Trinity Biotech Amax CS190
Trinity Biotech Amax CS400
Trinity Biotech Coag-A-Mate Max
Trinity Biotech KC 40, 4A, 1A Series
Trinity Biotech MDA 180
Trinity Biotech Coag-A-Mate MTX
Trinity Biotech Coag-A-Mate RA4
Trinity Biotech Coag-A-Mate XC/Plus
Trinity Biotech Coag-A-Mate XM

D. Major in Vitro Diagnostic Technologies and Their Potential Applications

1. Chromogenic Substrates

2. Monoclonal and Polyclonal Antibodies

3. Immunoassays
a. Applications
b. Technological Principle
c. Enzyme Immunoassays (EIA)
Overview
ELISA
EMIT
Dot Immunobinding Assays
Capillary Immunoassays
Enzyme Amplification
Electrochemical Immunoassay
d. Fluorescent Immunoassays
Fluorescence Polarization
Time-Resolved Pulse Fluorescence
Fluorescence Lifetime
e. Latex Agglutination
f. Immunoprecipitation

4. Microcomputers

5. Automation

6. Robotics

7. DNA Probes
a. Overview
b. Amplification Methods
PCR
Ligase Chain Reaction
Branched DNA
Q-Beta Replicase
NASBA
SDA
3 SR
HPA
Two-Tiered System
LAT

8. Artificial Intelligence

9. Dry Chemistry

10. Biosensors

III. France: Test Volume Forecasts by Market Segment

IV. Germany: Test Volume Forecasts by Market Segment

V. Italy: Test Volume Forecasts by Market Segment

VI. Japan: Test Volume Forecasts by Market Segment

VII. Spain: Test Volume Forecasts by Market Segment

VIII. UK: Test Volume Forecasts by Market Segment

IX. USA: Test Volume Forecasts by Market Segment

X. Design Criteria For Decentralized Testing Products

XI. Alternative Market Penetration Strategies

A. Internal Development

B. Collaborative Arrangements

C. University Contracts

D. Distribution Strategies for Decentralized Testing Markets

1. Marketing Approaches
2. Product Complexity
3. Customer Preference
4. Established Suppliers
5. Emerging Suppliers
6. Major Types Of Distributors
7. Market Segmentation

XII. Potential Market Entry Barriers and Risks

A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

XIII. Competitive Assessments

Abbott
American Diagnostica
Avocet Medical
Axis-Shield
Beckman Coulter
Becton Dickinson
Bio/Data Corporation
Biosite
Chrono-Log
Corgenix Medical
Diagnostica Stago
Helena Laboratories
HYPEN BioMed
Instrumentation Laboratory
ITC
Nanogen
Roche
Siemens
Sienco
Sysmex
Thermo Fischer
Trinity Biotech
ZyCare

List of Tables

Major Companies Developing or Marketing Antithrombin III Tests
France
Antithrombin III Test Volume Forecasts by Market Segment
Germany
Antithrombin III Test Volume Forecasts by Market Segment
Italy
Antithrombin III Test Volume Forecasts by Market Segment
Japan
Antithrombin III Test Volume Forecasts by Market Segment
Spain
Antithrombin III Test Volume Forecasts by Market Segment
U.K.
Antithrombin III Test Volume Forecasts by Market Segment
U.S.A.
Antithrombin III Test Volume Forecasts by Market Segment