Wound Closure Devices - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2018

This research provides key data, information and analysis on the global wound closure devices market. The report provides market landscape, competitive landscape and market trends information on the wound closure devices market. The report provides comprehensive information on the key trends affecting the market, and key analytical content on the market dynamics. The report also reviews the competitive landscape and technology offerings. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData’s team of industry experts.

Scope

• Key geographies covered include the US, Canada, the UK, Germany, France, Italy, Spain, Japan, China, India, Australia, and Brazil.
• Key segments covered include hemostats, tissue sealants, wound closure strips, mechanical stapling devices and ligating clips.
• Annualized market revenues data from 2004 to 2011, forecast forward for seven years to 2018. Company shares data for 2011.
• Qualitative analysis of key market trends, market drivers, and restraints by each segment within wound closure devices market.
• The report also covers information on the leading market players, the competitive landscape, and the leading pipeline products and technologies.
• Key players covered include Covidien plc, Ethicon and Baxter International.

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Additional Info:

Cosmetic Surgery Enhances Wound Closure Devices Market in the US

The growing popularity of cosmetic procedures is the main factor behind a noteable increase in surgical procedures and rising revenue from the global wound closure devices market, according to a new report by business intelligence expert GlobalData.

This new research shows that cosmetic surgery is playing a greater role in the growing number of surgeries being carried out, catching up to the numbers of people undergoing life-saving procedures for cardiovascular, orthopedic and laparoscopic issues. This, together with a globally aging population, increasing numbers of sports injuries, and high numbers of road accidents in emerging countries is maintaining a high demand for surgery and wound closure devices.

The US is the largest wound closure devices market in the world, primarily driven by an increasing number of surgeries. Further growth is expected to occur due to increasing cases of cosmetic surgeries, while being encouraged, to a lesser extent, by an increase in the number of elderly and technological innovations occurring in the field.

According to statistics released by the American Society for Aesthetic Plastic Surgery (ASAPS) in April 2011, the demand for plastic surgery procedures increased by 9% in 2010, and has grown by 155% since 1997.

About 9.5 million plastic surgery procedures were performed in the US in 2010, of which procedures performed on women accounted for 92%. During 2010, roughly $6.6 billion was spent by Americans on cosmetic surgery, with breast augmentation, lipoplasty, abdominoplasty, eyelid surgery and breast reductions representing the most popular procedures.

The craze for surgical self-improvement shows no signs of abating, leading to mass profits for related medical markets. As a result, GlobalData expects to see more companies rushing to invest in this area to ensure a healthy cut of the profits.

The global wound closure devices market was valued at $3.3 billion in 2011 and is forecast to grow at a Compound Annual Growth Rate (CAGR) of 4.9% to reach $4.6 billion in 2018. The US wound closure devices market was valued at $1.3 billion in 2011 and is expected to grow at a CAGR of 4.2% to reach $1.7 billion in 2018.

1 Table of Contents 3
1.1 List of Tables 5
1.2 List of Figures 6

2 Introduction 8
2.1 GlobalData Report Guidance 8

3 Wounds - Overview 9
3.1 Introduction 9
3.1.1 Types of Wounds 9
3.1.2 Wound Healing Stages 10
3.1.3 Factors Affecting Wound Healing 11

4 Wound Closure Devices - Overview 13
4.1 Hemostats 13
4.1.1 Collagen Based Hemostats 13
4.1.2 Oxidized Regenerated Cellulose Based Hemostats 13
4.1.3 Thrombin Based Hemostats 13
4.2 Ligating Clips 14
4.3 Mechanical Stapling Devices 14
4.4 Tissue Sealants 14
4.4.1 External Sealants 14
4.4.2 Internal Sealants 14
4.5 Wound Closure Strips 14

5 Wound Closure Devices - Global Market Characterization 15
5.1 Wound Closure Devices Market, Global, Revenue ($bn), Historic,  2004 –2011 15
5.2 Wound Closure Devices Market, Global, Revenue ($bn), Forecast, 2011–2018 16
5.3 Global Wound Closure Devices Market, Key Trends 17
5.3.1 Wound Closure Devices Market is Experiencing Shift towards the Use of More Advanced Devices Such as Hemostats and Tissue Sealants 17
5.3.2 Combination Hemostats are Witnessing Significant Adoption in the Wound Closure Devices Market 18
5.3.3 Cyanoacrylate Glue is Preferred by Surgeons for their Anti-Microbial Properties 20
5.4 Global Wound Closure Devices, Market Dynamics 20
5.4.1 Market Drivers 21
5.4.2 Market Restraints 32

6 Global Wound Closure Devices Market - Analysis by Segment 34
6.1 Hemostats Market, Global, Revenue ($m), Historic, 2004–2011 34
6.2 Hemostats Market, Global, Revenue ($m), Forecast, 2011–2018 35
6.2.1 Market Driver 36
6.2.2 Market Restraint 36
6.3 Ligating Clips Market, Global, Revenue ($m), Historic, 2004–2011 37
6.4 Ligating Clips Market, Global, Revenue ($m), Forecast, 2011–2018 38
6.5 Mechanical Stapling Devices Market, Global, Revenue ($m), Historic, 2004–2011 39
6.6 Mechanical Stapling Devices Market, Global, Revenue ($m), Forecast, 2011–2018 40
6.6.1 Market Drivers 41
6.6.2 Market Restraint 41
6.7 Tissue Sealants Market, Global, Revenue ($m), Historic, 2004–2011 42
6.8 Tissue Sealants Market, Global, Revenue ($m), Forecast, 2011–2018 43
6.8.1 Market Driver 44
6.8.2 Market Restraint 44
6.9 Wound Closure Strips Market, Global, Revenue ($m), Historic, 2004–2011 45
6.10 Wound Closure Strips Market, Global, Revenue ($m), Forecast, 2011–2018 46
6.10.1 Market Driver 47
6.10.2 Market Restraint 47

7 Global Wound Closure Devices Market - Analysis and Forecasts by Country 48
7.1 Wound Closure Devices Market, The US, Revenue ($m), Historic, 2004–2011 48
7.2 Wound Closure Devices Market, The US, Revenue ($m), Forecast, 2011–2018 49
7.3 Wound Closure Devices Market, Canada, Revenue ($m), Historic, 2004–2011 50
7.4 Wound Closure Devices Market, Canada, Revenue ($m), Forecast, 2011–2018 51
7.5 Wound Closure Devices Market, The UK, Revenue ($m), Historic, 2004–2011 52
7.6 Wound Closure Devices Market, The UK, Revenue ($m), Forecast, 2011–2018 53
7.7 Wound Closure Devices Market, Germany, Revenue ($m), Historic, 2004–2011 54
7.8 Wound Closure Devices Market, Germany, Revenue ($m), Forecast, 2011–2018 55
7.9 Wound Closure Devices Market, France, Revenue ($m), Historic, 2004–2011 56
7.10 Wound Closure Devices Market, France, Revenue ($m), Forecast, 2011–2018 57
7.11 Wound Closure Devices Market, Italy, Revenue ($m), Historic, 2004–2011 58
7.12 Wound Closure Devices Market, Italy, Revenue ($m), Forecast, 2011–2018 59
7.13 Wound Closure Devices Market, Spain, Revenue ($m), Historic, 2004–2011 60
7.14 Wound Closure Devices Market, Spain, Revenue ($m), Forecast, 2011–2018 61
7.15 Wound Closure Devices Market, Japan, Revenue ($m), Historic, 2004–2011 62
7.16 Wound Closure Devices Market, Japan, Revenue ($m), Forecast, 2011–2018 63
7.17 Wound Closure Devices Market, China, Revenue ($m), Historic, 2004–2011 64
7.18 Wound Closure Devices Market, China, Revenue ($m), Forecast, 2011–2018 65
7.19 Wound Closure Devices Market, India, Revenue ($m), Historic, 2004–2011 66
7.20 Wound Closure Devices Market, India, Revenue ($m), Forecast, 2011–2018 67
7.21 Wound Closure Devices Market, Australia, Revenue ($m), Historic, 2004–2011 68
7.22 Wound Closure Devices Market, Australia, Revenue ($m), Forecast, 2011–2018 69
7.23 Wound Closure Devices Market, Brazil, Revenue ($m), Historic, 2004–2011 70
7.24 Wound Closure Devices Market, Brazil, Revenue ($m), Forecast, 2011–2018 71

8 Global Wound Closure Devices Market - Competitive Assessment 72
8.1 Wound Closure Devices Market, Global, Key Market Participants 73
8.1.1 Covidien Plc. 73
8.1.2 Ethicon Inc. (Subsidiary of Johnson & Johnson) 76
8.1.3 Baxter International Inc. 79

9 Wound Closure Devices - Pipeline Assessment 82
9.1 Wound Closure Devices, Pipeline by Phase of Development, 2011 82
9.2 Pipeline Assessment, Hemostats, 2011 83
9.2.1 Key Pipeline Products, Hemostats 84
9.3 Pipeline Assessment, Tissue Sealants, 2011 89
9.3.1 Key Pipeline Products, Tissue Sealants 91
9.4 Pipeline Assessment, Other Wound Closure Devices, 2011 97

10 Global Wound Closure Devices Market - Strategic Deals Analysis 99
10.1 Key Deals, Wound Closure Devices Market 99
10.1.1 Stryker Completes Acquisition of Orthovita 99
10.1.2 CryoLife Enters Into An Agreement With Starch Medical 99
10.1.3 Z-Medica Signs An Agreement With Nihon Kohden 99
10.1.4 HemCon Medical Technologies Signs Licensing Agreement With Zeria Pharmaceuticals 100

11 Appendix 101
11.1 Market Definitions 101
11.1.1 Wound Closure Devices 101
11.2 Abbreviations (in alphabetical order) 102
11.3 Sources 103
11.4 Research Methodology 105
11.4.1 Secondary Research 105
11.4.2 Primary Research 106
11.4.3 Models 106
11.4.4 Forecasts 106
11.4.5 Expert Panel 107
11.5 GlobalData Consulting 107
11.6 Contact Us 107
11.7 Disclaimer 107

1.1 List of Tables
Table 1: Wound Closure Devices Market, Global, Revenue ($bn), 2004–2011 15
Table 2: Wound Closure Devices Market, Global, Revenue ($bn), 2011–2018 16
Table 3: Studies Suggesting Efficacy of Combination Hemostats, 2007-2011 18
Table 4: Combination Hemostats Available in the Market 19
Table 5: Cyanoacrylate Glue Studies, 2008-2011 20
Table 6: Top Cosmetic Surgery Procedures, the US, 1997-2010 21
Table 7: Cosmetic Surgery Procedures, the UK, 2008-2010 22
Table 8: Operations on the Cardiovascular System, The US, 2007-2009 23
Table 9: Laparoscopic Surgeries, Europe (France, Germany, Italy, Spain and the UK) 2005-2009 24
Table 10: Orthopedic Procedures (‘000s), The US, 1997-2009 25
Table 11: Sports Related Injuries* (millions), The US, 2007-2010 26
Table 12: Studies with the Use of Fibrin Sealants for Treatment of Sports Injuries, 2007 and 2010 27
Table 13: Road Traffic Fatalities in India, 1997-2007 28
Table 14: Number of Deaths in Traffic Accidents, Brazil, 2002-2010 28
Table 15: Total Number of Traffic Accidents, Russian Federation 2000-2008 29
Table 16: Age-Wise Rate of Procedures Per 10,000 Population, The US, 2009 29
Table 17: All Procedures in 65 Years and Older Population, The US, 2007-2009 30
Table 18: Population Above 65 years, 2010-2030 31
Table 19: Number of Orthopedic Surgeons in the US, 2002–2010 33
Table 20: Hemostats Market, Global, Revenue ($m), 2004–2011 34
Table 21: Hemostats Market, Global, Revenue ($m), 2011–2018 35
Table 22: Safety and Efficacy Studies for Hemostats, 2009-2012 36
Table 23: Ligating Clips Market, Global, Revenue ($m), 2004–2011 37
Table 24: Ligating Clips Market, Global, Revenue ($m), 2011–2018 38
Table 25: Mechanical Stapling Devices Market, Global, Revenue ($m), 2004–2011 39
Table 26: Mechanical Stapling Devices Market, Global, Revenue ($m), 2011–2018 40
Table 27: Absorbable Stapler Study, 2009 41
Table 28: Tissue Sealants Market, Global, Revenue ($m), 2004–2011 42
Table 29: Tissue Sealants Market, Global, Revenue ($m), 2011–2018 43
Table 30: Tissue Sealants and Hemostats Market Revenues ($m), Global, 2004-2018 44
Table 31: Wound Closure Strips Market, Global, Revenue ($m), 2004–2011 45
Table 32: Wound Closure Strips Market, Global, Revenue ($m), 2011–2018 46
Table 33: Wound Closure Devices Market, The US, Revenue ($m), 2004–2011 48
Table 34: Wound Closure Devices Market, The US, Revenue ($m), 2011–2018 49
Table 35: Wound Closure Devices Market, Canada, Revenue ($m), 2004–2011 50
Table 36: Wound Closure Devices Market, Canada, Revenue ($m), 2011–2018 51
Table 37: Wound Closure Devices Market, The UK, Revenue ($m), 2004–2011 52
Table 38: Wound Closure Devices Market, The UK, Revenue ($m), 2011–2018 53
Table 39: Wound Closure Devices Market, Germany, Revenue ($m), 2004–2011 54
Table 40: Wound Closure Devices Market, Germany, Revenue ($m), 2011–2018 55
Table 41: Wound Closure Devices Market, France, Revenue ($m), 2004–2011 56
Table 42: Wound Closure Devices Market, France, Revenue ($m), 2011–2018 57
Table 43: Wound Closure Devices Market, Italy, Revenue ($m), 2004–2011 58
Table 44: Wound Closure Devices Market, Italy, Revenue ($m), 2011–2018 59
Table 45: Wound Closure Devices Market, Spain, Revenue ($m), 2004–2011 60
Table 46: Wound Closure Devices Market, Spain, Revenue ($m), 2011–2018 61
Table 47: Wound Closure Devices Market, Japan, Revenue ($m), 2004–2011 62
Table 48: Wound Closure Devices Market, Japan, Revenue ($m), 2011–2018 63
Table 49: Wound Closure Devices Market, China, Revenue ($m), 2004–2011 64
Table 50: Wound Closure Devices Market, China, Revenue ($m), 2011–2018 65
Table 51: Wound Closure Devices Market, India, Revenue ($m), 2004–2011 66
Table 52: Wound Closure Devices Market, India, Revenue ($m), 2011–2018 67
Table 53: Wound Closure Devices Market, Australia, Revenue ($m), 2004–2011 68
Table 54: Wound Closure Devices Market, Australia, Revenue ($m), 2011–2018 69
Table 55: Wound Closure Devices Market, Brazil, Revenue ($m), 2004–2011 70
Table 56: Wound Closure Devices Market, Brazil, Revenue ($m), 2011–2018 71
Table 57: Covidien Plc., Key Marketed Products 73
Table 58: Covidien Plc, Skin Stapler Device Portfolio 74
Table 59: Ethicon Inc., Key Marketed Products 76
Table 60: Ethicon Inc., Pipeline Products 78
Table 61: Baxter International Inc., Key Marketed Products 79
Table 62: Wound Closure Devices, Pipeline by Phase of Development, 2011 82
Table 63: Pipeline Assessment, Hemostats, 2011 83
Table 64: Fibrin Pad, Clinical Trial Details 84
Table 65: Fibrin Pad, Clinical Trial Details 85
Table 66: Fibrocaps, Clinical Trial Details 87
Table 67: Fibrocaps, Clinical Trial Details 87
Table 68: Pipeline Assessment, Tissue Sealants, 2011 89
Table 69: Bio-Seal Lung Biopsy Tract Plug System, Clinical Trial Details 91
Table 70: Bio-Seal Lung Biopsy Tract Plug System, Clinical Trial Details 92
Table 71: Dural Membrane Sealant, Clinical Trial Details 93
Table 72: Seraffix LTB, Clinical Trial Details 96
Table 73: Pipeline Assessment, Other Wound Closure Devices, 2011 97

1.2 List of Figures
Figure 1: Surgical Wounds Classification 10
Figure 2:  Wound Healing Stages 10
Figure 3:  Wound Closure Devices: Market Segmentation 13
Figure 4:  Wound Closure Devices Market, Global, Revenue ($bn), 2004–2011 15
Figure 5:  Wound Closure Devices Market, Global, Revenue ($bn), 2011–2018 16
Figure 6: Wound Closure Devices, Comparison by Segment, 2004-2018 17
Figure 7: Advantages Offered by Hemostats and Tissue Sealants 18
Figure 8:  Global Wound Closure Devices, Market Dynamics 20
Figure 9: Top Cosmetic Surgery Procedures, the US, 1997-2010 21
Figure 10: Cosmetic Surgery Procedures, the UK, 2008-2010 22
Figure 11:   Operations on the Cardiovascular System, The US, 2007-2009 23
Figure 12: Laparoscopic Surgeries, Europe (France, Germany, Italy, Spain and the UK) 2005-2009 24
Figure 13: Orthopedic Procedures (‘000s), The US, 1997-2009 25
Figure 14: Sports Related Injuries* (millions), The US, 2007-2010 26
Figure 15: Road Traffic Fatalities in India, 1997-2007 27
Figure 16: Number of Deaths in Traffic Accidents, Brazil, 2002-2010 28
Figure 17: Total Number of Traffic Accidents, Russian Federation 2000-2008 29
Figure 18: All Procedures in 65 Years and Older Population, The US, 2007-2009 30
Figure 19: Comparison of Minimally Invasive Surgery and Invasive (Open) Surgery 32
Figure 20:  Hemostats Market, Global, Revenue ($m), 2004–2011 34
Figure 21:  Hemostats Market, Global, Revenue ($m), 2011–2018 35
Figure 22:  Ligating Clips Market, Global, Revenue ($m), 2004–2011 37
Figure 23:  Ligating Clips Market, Global, Revenue ($m), 2011–2018 38
Figure 24:  Mechanical Stapling Devices Market, Global, Revenue ($m), 2004–2011 39
Figure 25:  Mechanical Stapling Devices Market, Global, Revenue ($m), 2011–2018 40
Figure 26:  Tissue Sealants Market, Global, Revenue ($m), 2004–2011 42
Figure 27:  Tissue Sealants Market, Global, Revenue ($m), 2011–2018 43
Figure 28: Tissue Sealants and Hemostats Market Revenues ($m), Global, 2004-2018 44
Figure 29:  Wound Closure Strips Market, Global, Revenue ($m), 2004–2011 45
Figure 30:  Wound Closure Strips Market, Global, Revenue ($m), 2011–2018 46
Figure 31:  Wound Closure Devices Market, The US, Revenue ($m), 2004–2011 48
Figure 32:  Wound Closure Devices Market, The US, Revenue ($m), 2011–2018 49
Figure 33:  Wound Closure Devices Market, Canada, Revenue ($m), 2004–2011 50
Figure 34:  Wound Closure Devices Market, Canada, Revenue ($m), 2011–2018 51
Figure 35:  Wound Closure Devices Market, The UK, Revenue ($m), 2004–2011 52
Figure 36:  Wound Closure Devices Market, The UK, Revenue ($m), 2011–2018 53
Figure 37:  Wound Closure Devices Market, Germany, Revenue ($m), 2004–2011 54
Figure 38:  Wound Closure Devices Market, Germany, Revenue ($m), 2011–2018 55
Figure 39:  Wound Closure Devices Market, France, Revenue ($m), 2004–2011 56
Figure 40:  Wound Closure Devices Market, France, Revenue ($m), 2011–2018 57
Figure 41:  Wound Closure Devices Market, Italy, Revenue ($m), 2004–2011 58
Figure 42:  Wound Closure Devices Market, Italy, Revenue ($m), 2011–2018 59
Figure 43:  Wound Closure Devices Market, Spain, Revenue ($m), 2004–2011 60
Figure 44:  Wound Closure Devices Market, Spain, Revenue ($m), 2011–2018 61
Figure 45:  Wound Closure Devices Market, Japan, Revenue ($m), 2004–2011 62
Figure 46:  Wound Closure Devices Market, Japan, Revenue ($m), 2011–2018 63
Figure 47:  Wound Closure Devices Market, China, Revenue ($m), 2004–2011 64
Figure 48:  Wound Closure Devices Market, China, Revenue ($m), 2011–2018 65
Figure 49:  Wound Closure Devices Market, India, Revenue ($m), 2004–2011 66
Figure 50:  Wound Closure Devices Market, India, Revenue ($m), 2011–2018 67
Figure 51:  Wound Closure Devices Market, Australia, Revenue ($m), 2004–2011 68
Figure 52:  Wound Closure Devices Market, Australia, Revenue ($m), 2011–2018 69
Figure 53:  Wound Closure Devices Market, Brazil, Revenue ($m), 2004–2011 70
Figure 54:  Wound Closure Devices Market, Brazil, Revenue ($m), 2011–2018 71
Figure 55: Wound Closure Devices Market, Global, Key Company Shares* (%), 2011 72
Figure 56:  Wound Closure Devices, Pipeline by Phase of Development, 2011 82
Figure 57: Pipeline Analysis, Hemostats, 2011 83
Figure 58:  Pipeline Analysis, Tissue Sealants, 2011 89