Future Italian Blood Banking Market: Growth Opportunities and Business Expansion Strategies

This report presents a comprehensive analysis of the Italian blood banking market, including:

• Major issues pertaining to the Italian blood banking practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years.
• Ten-year volume and sales forecasts for 40 blood typing, grouping and infectious disease screening tests, including NAT procedures performed in Italian blood banks hospitals, and commercial laboratories.
• Annual placements and installed base estimates for major automated and semi-automated analyzers.
• Review of current instrumentation technologies, and a feature comparison of over 20 analyzers.
• Ten-year reagent and instrument sales forecasts.
• Sales and market shares of leading reagent and instrument suppliers.
• Review of current and emerging technologies, and their potential market applications.
• Product development opportunities for instruments, consumables, and auxiliary products.
• Profiles of major current and emerging suppliers, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements, and business strategies.
• Business opportunities and strategic recommendations for suppliers.

Table of Contents

Worldwide Technology and Market Overview

A. Major Blood Typing, Grouping and Infectious
Disease Screening Tests

1. Blood Typing and Grouping Tests
a. ABO
b. Antibody Panels
c. Antibody Screening
d. Antigen Typing
e. Antiglobulin Test
f. Crossmatch
g. HLA Typing
h. Rh
i. Other Blood Groups

2. Infectious Disease Screening Tests
a. AIDS
Structure and Composition
Classification
HIV2 Infection
Origin of AIDS
Animal Lentivirus Systems
Virus Receptors
HIV Infections in Humans
Pathogenesis & Pathology
Overview of Course of HIV Infection
CD4T Lymphocytes and Memory Cells
Monocytes and Macrophages
Lymphoid Organs
Neural Cells
Viral Coinfections
Clinical Findings
Plasma Viral Load
Pediactric AIDS
Neurologic Disease
Opportunistic Infections
Protozoa
Fungi
Bacteria
Viruses
Cancer
Immunity
Laboratory Diagnosis
Virus Isolation
Serology
Detection of Viral Nucleic Acid or Antigens
Epidemiology
Worldwide Spread of AIDS
United States
Routes of Transmission
Prevention, Treatment, And Control
Antiviral Drugs
Vaccines Against HIV
Transmission of HIV in Blood Products
HIV Transmission in Transplant and
Artificial Insemination Recipients
Diagnostic Tests
Enzyme Immunoassay Interpretation
Specificity, Sensitivity, and Predictive
Value of Enzyme Immunoassay
Competition Assays
Western Blot Technique
ImmunoFluorescence Assay (IFA)
Radioimmunoprecipitation
HIV1/HIV2 Combination Testing
Methods of HIVAntigen Detection
Antigen Assays and Blood Screening
Urine Tests
DNA Probes
Overview
Quantitative Polymerase Chain Reaction
In Situ PCR
Needed Improvements
Viral Load/Drug Resistance Testing
Genotype and Phenotype Testing
Blood Banking Considerations
b. Hepatitis
Hepatitis A
Hepatitis B
Structure and Composition
Replication of Hepatitis B Virus
Hepatitis C
Hepatitis D (Delta Hepatitis)
Hepatitis E
Hepatitis G
Hepatitis Virus Infections In Humans
Pathology
Clinical Findings
Laboratory Features
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
VirusHost Immune Reactions
Epidemiology
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D (Delta Agent)
Vaccines and Drugs
c. Cytomegalovirus
Background
Chorioretinitis
Gastrointestinal
Central Nervous System Disease
Diagnostic Tests
Vaccines and Drugs
d. Syphilis
Background
Diagnostic Tests
Vaccines and Drugs
e. West Nile Virus
Background
Clinical Syndromes
Diagnostic Tests
Vaccines and Drugs
f. Parvovirus B19
Microbiology
Epidemiology
Clinical Syndromes
Erythema Infectiosum Slapped (cheek)
Adult Polyarthropathy
Transient Aplastic Crisis
Transient Pancytopenia
Red Cell Aplasia in the Immunocompromised
Perinatal Infections
Diagnosis
Treatment
g. CreutzfeldtJakob’s Disease
Background
Transmission
Diagnostic Tests
Major Commercial and Academic Players
Bayer
Disease Sciences/BioTec Global
Imperial College School of Medicine
OrthoClinical Diagnostics
Pall
ProMetic Life Sciences
Proteome Sciences/Idexx
QOne Biotech
Serono
U.S. Agricultural Research Service
Drugs
Vaccines
h. Malaria
i. Chagas Disease
j. Babesiosis

3. Pathogen Reduction

4. Leukocyte Reduction
Background
Methods

B. Instrumentation Review

Introduction
1. Abbott Prism
2. Abbott Quantum II
3. Abbott Commander
4. BioMeriuex BacT/Alert
5. Dade Behring Quadriga
6. Dade Behring BEP 2000
7. Grifols Diana
8. Immucor ABS2000
8. Immucor Galile
10. Immucor Rosys Plato
11. Olympus PK7100
12. Olympus PK7200
13. Olympus PK80
14. Olympus BloodTrack Courier
15. Ortho AutoVue/ProVue
16. Ortho Summit Processor
17. Tecan ELPHAtyper
18. Tecan Hemotyper
19. Tecan MegaFlex
20. Tecan MiniSwift

C. Major in Vitro Diagnostic Technologies
And Their Potential Applications

1. Molecular Diagnostics
a. Overview
b. NAT

2. Monoclonal and Polyclonal Antibodies

3. Immunoassays
a. Technological Principle
b. Enzyme Immunoassays (EIA)
Overview
ELISA
Enzyme Amplification
c. Fluorescent Immunoassays
Fluorescence Polarization
d. Luminescence
Chemiluminescence
Bioluminescence
e. Latex Agglutination
f. Immunoprecipitation

4. Microtitration Plates

5. Microcomputers

6. Automation

7. Lasers

8. Robotics

9. Artificial Intelligence

10. Synthetic Red Cell Substitutes

11. Genetically Engineered Blood Components
a. Albumin
b. Factor VIII
c. Alpha2 Antiplasmin
d. Antithrombin III
e. Factor IX
f. Von Willebrand's Factor
g. Fibrinogen
h. tPA

12. Blood Preservation

13. Autologous Blood Transfusion/Freezing

D. Worldwide Market Overview
1. Business Environment
2. Market Structure
3. Market Size and Growth

Italy
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers’
Consumable Sales, Instrument Placements,
Installed Base and Market Shares

Major Product Development Opportunities
A. Blood Typing And Grouping
B. Infectious Disease Screening
C. Auxiliary

Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts

Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints

Competitive Assessments
Abbott
Beckman Coulter
Biokit
BioMerieux
BioRad
Bioscot
Biotest
Chiron
Diagast
Diamed
DiaSorin
Fujirebio
GenProbe
Gradipore
Grifols
ImmucorGamma
Innogenetics
Orchid Biosciences
OrthoClinical Diagnostics
Proteome Sciences
Roche
Siemens
Tecan

Appendix: Assumed Currency Exchange Rates

THE ITALIAN BLOOD BANKING MARKET THROUGH 2015

List of Tables

Major Companies Developing or Marketing
Blood Typing and Grouping Tests
Major Companies Developing or Marketing
HLA Typing Tests
Major Companies Developing or Marketing
AIDS Tests
Major Companies Developing or Marketing
Hepatitis Tests
Major Companies Developing or Marketing
CMV Tests
Major Companies Developing or Marketing
Syphilis Tests
Major Companies Developing or Marketing
Blood Bank Analyzers
Worldwide, All Market Segments, Facilities
Performing Blood Bank Tests By Country
Worldwide, All Market Segments, Total
Blood Typing and Grouping Test Volume Forecast
By Country
Worldwide, All Market Segments, Total
Infectious Disease Screening Test Volume Forecast
Worldwide, All Market Segments, Total
Blood Typing and Grouping Reagent Market Forecast
By Country
Worldwide, All Market Segments, Total
Infectious Disease Reagent Market Forecast By
Country

Executive Summary Table: Italy, Total Blood Bank
Test Volume and Reagent Sales Forecast By Test
Category
Italy, Facilities Performing Blood
Bank Tests By Market Segment
Italy, Hospital Laboratories Performing
Blood Bank Tests By Bed Size
Italy, Commercial/Private Laboratories
Performing Blood Bank Tests By Annual
Test Volume
Italy, All Market Segments Blood Typing
and Grouping Test Volume By Market Segment
Italy, All Market Segments Blood Typing
and Grouping Test Volume Forecast
Italy, Hospital Laboratories Blood
Typing and Grouping Test Volume Forecast
Italy, Blood Banks Blood Typing
and Grouping Test Volume Forecast
Italy, Commercial/Private Laboratories
Blood Typing and Grouping Test Volume Forecast
Italy, All Market Segments Infectious
Disease Screening Test Volume Forecast By Market
Segment
Italy, All Market Segments Infectious
Disease Screening Test Volume Forecast
Italy, Blood Banks Infectious Disease
Screening Test Volume Forecast
Italy, Commercial/Private Laboratories
Infectious Disease Screening Test Volume Forecast
Italy, Hospital Laboratories Infectious
Disease Screening Test Volume Forecast
Italy, All Market Segments Blood Typing
and Grouping Reagent Market Forecast By Market
Segment
Italy, All Market Segments Blood Typing
and Grouping Reagent Market Forecast By Major
Test
Italy, Hospital Laboratories Blood
Typing and Grouping Reagent Market Forecast By
Major Test
Italy, Blood Banks Blood Typing and
Grouping Reagent Market Forecast By Major Test
Italy, Commercial/Private Laboratories
Blood Typing and Grouping Reagent Market Forecast
By Major Test
Italy, All Market Segments Infectious
Disease Screening Reagent Market Forecast By Market
Segment
Italy, All Market Segments Infectious
Disease Screening Reagent Market Forecast By Test
Italy, Blood Banks Infectious Disease
Screening Reagent Market Forecast By Test
Italy, Commercial/Private Laboratories Infectious
Disease Screening Reagent Market Forecast By Test
Italy, Hospital Laboratories
Infectious Disease Screening Reagent Market Forecast
By Test
Italy, Major Suppliers of Blood Typing
and Grouping Reagents Estimated Sales and
Market Shares
Italy, HIV/Hepatitis Blood Screening Market,
Reagent Sales By Major Supplier
Italy, HIV/Hepatitis NAT Market,
Reagent Sales By Major Supplier
Italy, Major Suppliers of Blood Bank
Automated Analyzers, Estimated Placements and
Installed Base By Supplier and Model